. A dissertation on the cynanche maligna. , the face and neck put ona very bloated appearance, respiration grow morelaborious, with a peculiar kind of catching thebreath, or double breathing, and an anxiety offive or six minutes continuance come on threeor four times in an hour, such as induces the pa-tient to bite his hands and arms, death may be ex-pected on the fifth day. This alteration in thedisorder is sudden, and not to be foreseen ; and,when it takes place, I never was so fortunate asto find a medicine, that would prevent, or evenretard the fatal catastrophe. The skin, after death,woul


. A dissertation on the cynanche maligna. , the face and neck put ona very bloated appearance, respiration grow morelaborious, with a peculiar kind of catching thebreath, or double breathing, and an anxiety offive or six minutes continuance come on threeor four times in an hour, such as induces the pa-tient to bite his hands and arms, death may be ex-pected on the fifth day. This alteration in thedisorder is sudden, and not to be foreseen ; and,when it takes place, I never was so fortunate asto find a medicine, that would prevent, or evenretard the fatal catastrophe. The skin, after death,would immediately turn very black, and some-times, previous thereto, would be spotted in ma-ny places with green. Is there a medicine in themateria medica, which would have been so like-ly to put a stop to these putrid and fatal symp-tom?, as the Peruvian bark ? The bark, when used in this disease, is to begiven from the beginning in substance, and inlarge quantities as the age of the patient, and c:circumstances, will admit. Dr. Cullen sa-v. C 7 .1 crood effects are to be expected from it almost on«ly when given in this way. It should always begiven in vinous or distilled spirits, when these canbe procured ; in this way the less quantity of barkis required ; it sits more easily upon the stomach,and its effects are more sudden. Dr. Moore, speaking of the Cynanche Malig-na, says, I have seen the weakness so great inthis disease, that the patient could not sit up inhis bed, that his throat might be accurately exam-ined, without danger of fainting ; yet after a fewdoses of the bark, mixed with Port or Madeirawine, his pulse became stronger and fuller, andhe raised himself with little assistance, and sat upfirmly ; but in others, in nearly the same situa-tion, double the quantity of the bark taken inany of the simple waters, hardly produced thesame effect, and never so soon ; and where winewas not to be got, or could not be afforded, rumor brandy diluted seemed in all respects equival


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