. Applied immunology : the practical application of sera and bacterins prophylactically, diagnostically, and therapeutically. Gonorrhceal allergic reaction, demonstrating the papulo-erythematoua cutaneousresponse on the third day after the intradermic injection of one cubic millimetre of akilled polyvalent suspension of gonococci. SPECIFIC BACTERIAL REACTIONS 191 inoculations of dead gonococci and suggested the useof gonococcic bacterin in this capacity. At the timeof this report, one of the authors (Thomas) had beenutilizing an alternation of subcutaneous injections oftuberculin, gonococcic,


. Applied immunology : the practical application of sera and bacterins prophylactically, diagnostically, and therapeutically. Gonorrhceal allergic reaction, demonstrating the papulo-erythematoua cutaneousresponse on the third day after the intradermic injection of one cubic millimetre of akilled polyvalent suspension of gonococci. SPECIFIC BACTERIAL REACTIONS 191 inoculations of dead gonococci and suggested the useof gonococcic bacterin in this capacity. At the timeof this report, one of the authors (Thomas) had beenutilizing an alternation of subcutaneous injections oftuberculin, gonococcic, streptococcic, pneumococcicand staphylococcic bacterins in the differential diag-nosis of the etiological bacterium in obscure articularaffections, with a view to the determination of thecorrect biological therapeutic agent. Contrary toIrons apparent greater reliance on the general andfocal reaction, Thomas attached more significance tothe local reaction at the injectional site, employingmuch smaller doses, 100,000,000 instead of 500,000,-000 cocci. Recently the substitution of unheatedbouillon filtrate or a filtrate si


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Keywords: ., bookcentury1900, bookdecade1910, bookpublisherphila, bookyear1916