. Pharmaceutical bacteriology. Bacteriology; Disinfection and disinfectants. SEROLOGY—MANUFACTURE AND USE OF SERA AND VACCINES 263 From nine to twelve liter of blood are taken from the horse at one time and the bleeding is repeated four or five times at intervals of about six months The punctured wound is closed by keeping an artery forceps in position for a short time. E. Securing the Serum.—The blood tubes are set aside until the clot has formed and settled to the bottom. The clear serum is siphoned off into a large flask, per cent, of trikresol is added as a preservative and. Fig. 63.—


. Pharmaceutical bacteriology. Bacteriology; Disinfection and disinfectants. SEROLOGY—MANUFACTURE AND USE OF SERA AND VACCINES 263 From nine to twelve liter of blood are taken from the horse at one time and the bleeding is repeated four or five times at intervals of about six months The punctured wound is closed by keeping an artery forceps in position for a short time. E. Securing the Serum.—The blood tubes are set aside until the clot has formed and settled to the bottom. The clear serum is siphoned off into a large flask, per cent, of trikresol is added as a preservative and. Fig. 63.—Bleeding the horse after a maximum amount ot the antitoxin of diph- theria has been developed in the blood. The animals pay but little attention to the operation. to kill any germs that might be accidentally present, and then filtered through several thicknesses of filter paper, underpressure (suction). The perfectly clear, sterile and germ-free serum constitutes the antitoxin of diphtheria and is ready for use as soon as it is standardized and put into suitable containers. F. Standardizing the Antitoxin of Diphtheria.—Since the antitoxic va- lence of horse serum as above described varies somewhat, it is necessary to determine the quantitative value in order that physicians may know what amounts to administer in the treatment of diphtheria. The standard unit of strength now adopted by all civilized countries is the so-called. Please note that these images are extracted from scanned page images that may have been digitally enhanced for readability - coloration and appearance of these illustrations may not perfectly resemble the original Schneider, Albert, 1863-1928. Philadelphia, P. Blakiston's Son & Co.


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