. The collected papers of Joseph baron Lister . erum, forming a sort ^ See Lancet for March i6, 1867, p. 328 (p. 8 of this vohime). ON THE ANTISEPTIC SYSTEM 95 of pocket in the living tissues, which, when scraped with the edge of a knife,bled even at the very margin of the cavity. This appearance showed that thedeeper portions of the crust itself had been converted into living tissue. Forcavities formed during the process of aggregation, like those with clear liquidcontents in a Gruyere cheese, occur in the grumous mass which results fromthe action of carbolic acid upon blood ; and that which


. The collected papers of Joseph baron Lister . erum, forming a sort ^ See Lancet for March i6, 1867, p. 328 (p. 8 of this vohime). ON THE ANTISEPTIC SYSTEM 95 of pocket in the living tissues, which, when scraped with the edge of a knife,bled even at the very margin of the cavity. This appearance showed that thedeeper portions of the crust itself had been converted into living tissue. Forcavities formed during the process of aggregation, like those with clear liquidcontents in a Gruyere cheese, occur in the grumous mass which results fromthe action of carbolic acid upon blood ; and that which I had exposed hadevidently been one of these, though its walls were now alive and the dead, but nutritious mass, had served as a mould for the formation ofnew tissue, the growing elements of which had replaced the materials absorbed,so as to constitute a living solid of the same form. Hence it might have been anticipated that the ligatures of peritoneumand catgut placed on the calfs carotid would, after the expiration of a month,. Fig. 2.—The vessel seen in longitudinal section, magnified threediameters. From a camera-lucida sketch. A, the artery to the cardiacside of the ligature, kept free from clot by the stream of blood throughthe branch B. C, the coagulum filling the artery to the distal side of theligature, F, F. D, the middle and internal coats, somewhat thickenedand blended together within the grasp of the ligature. A, the externalcoat continuous in structure with the organized ligature. be found transformed into bands of living tissue. Such was, in truth, the case,as was apparent on closer examination. They had, indeed, a deceptive resem-blance to their former condition, from the persistence in their substance of theimpurities of the original materials, the dark adventitious particles being ofmineral nature incapable of absorption, so that they had remained as a sortof tattooing of the new structure. Nevertheless, a marked alteration in colourhad taken


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