The hygiene of transmissible diseases; their causation, modes of dissemination, and methods of prevention . s said to be differentiated from bacillus tuberculosis byspecial staining reactions. Though several authors (Bordoni-Ufreduzzi, Ducrey, and Campana) claim to have cultivatedthis organism, it is doubtful if it has ever been grown artifici-ally. In fact, such a number of efforts to culti\ate it fromskin-lesions by trustworthy investigators ha\c resulted infailure, that the general impression now is that the majorityof the bacilli seen in the tissues are dead. At all e\ents, oneof their mos
The hygiene of transmissible diseases; their causation, modes of dissemination, and methods of prevention . s said to be differentiated from bacillus tuberculosis byspecial staining reactions. Though several authors (Bordoni-Ufreduzzi, Ducrey, and Campana) claim to have cultivatedthis organism, it is doubtful if it has ever been grown artifici-ally. In fact, such a number of efforts to culti\ate it fromskin-lesions by trustworthy investigators ha\c resulted infailure, that the general impression now is that the majorityof the bacilli seen in the tissues are dead. At all e\ents, oneof their most frequent microscopical peculiarities is a con-spicuous degree of apparent degeneration. LEPROSY. 149 On microscopical examination with low magnifying powersof sections of leprous tissue stained by any of the methodsused for staining tubercle bacilli in tissues, the leprosy bacil-lus is detected usually in enormous numbers. It will beseen scattered through the tissue as smaller and largerclumps of individual bacilH (Fig. 17). On examining theseclumps under a high magnifying power, they will usually be. Fig. 17.—Schematic representation of section through a lepra nodule : leftside of picture gives appearance under low magnifying power ; right side, theappearance when highly magnified. In the latter the large lepra cells arediagrammatically indicated. found to represent single granulation-cells that are packedwith the bacilli—the so-called lepra-cells —of which alarge part of the new growth is composed. The bacilli areirregularly stained, often irregular in outline, beaded andbroken, and, as said, usually present the appearance ofdegeneration. The bacilli are also present in the secretionsthat may exude or be squeezed from the leprous nodule insitu. They have been found in the circulating blood, butonly in very small numbers. Sticker found them in the nasaldischarges from 128 out of 153 cases examined by him. Inonly 23 of these 153 cases did he find them in the
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Keywords: ., bookcentury1800, bookdecade1890, booksubject, booksubjectdiseases
