The pathology and surgical treatment of tumors . half of giant-cells. Many sarcomatacontain giant-cells, but when these cells do not predominate thetumor is designated according to the cell-elements which form the 576 PATHOLOGY AND TREATMENT OF TUMORS. greater bulk. A pure giant-celled sarcoma does not exist: we findat the same time between the giant-cells round cells, spindle-cells, orboth (Fig. 412). The intercellular substance is scanty, amorphous,or in the shape of fibrillse. The prototypes in normal tissue of thegiant-cells are the myeloplaqiies in the marrow of bone. Giant-celledsarcoma
The pathology and surgical treatment of tumors . half of giant-cells. Many sarcomatacontain giant-cells, but when these cells do not predominate thetumor is designated according to the cell-elements which form the 576 PATHOLOGY AND TREATMENT OF TUMORS. greater bulk. A pure giant-celled sarcoma does not exist: we findat the same time between the giant-cells round cells, spindle-cells, orboth (Fig. 412). The intercellular substance is scanty, amorphous,or in the shape of fibrillse. The prototypes in normal tissue of thegiant-cells are the myeloplaqiies in the marrow of bone. Giant-celledsarcoma is rare in children and in the aged, and is found most fre-quently in the lower jaw, the femur, and the tibia. The tumor, which isnot encapsulated, but is circumscribed, is of slow growth, of a red orbrownish color, and is not prone to ossify or degenerate. Cysts are produced by hemorrhage or by degenerative changes intumors of large size. The vascular supply of these tumors is so greatthat pulsation and bruit are frequently present (Fig. 413).. Fig. 413.—Myeloid cystic giant-celled sarcoma of the lower epiphysis of the femur, from a girl twenty-twoyears old; longitudinal section, one-half natural size (after Ziesing). The lower end of the tumor is roundand is covered by the articular cartilage {d)\ e, patella. The dark streak (a) indicates thickness and direc-tion of the secondary shell of bone, which can be traced a certain distance along the outer and inner surfacesof the shaft of the bone {a). The cyst-walls were smooth; some of the cysts contained serum, others extrav-asated blood {/). The bone-producing function of myeloid sarcoma is always limited,and in many cases is entirely wanting—a circumstance which frequentlyresults in pathological fracture. SARCOMA. S77 Round-cdled Sarcoma.—In this variety of sarcoma the round cellscompose the entire tumor or the bulk of the tumor, the balance beingrepresented by spindle-cells and a few giant-cells. Round-celled ismore mali
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Keywords: ., bookcentury1800, bookdecade1890, booksubjectneoplas, bookyear1895
