The pathology and surgical treatment of tumors . and these ramifications can befelt under the skin (Fig. 369). The tumorconsists of a fibrous framework throughwhich run bundles of nerve-fibres, someof them completely medullated, othersonly partially so (Fig. 370). Large gan-glion-cells with characteristic nuclei andnucleoli are also sometimes found im-bedded in the tumor-mass. Waldenstrom,who doubts the correctness of Virchowsidea that a neuroma is composed largelyof nerve-fibres without medullary sheath,regards them as fibromata originating fromthe interstitial connective tissue. Westphal has
The pathology and surgical treatment of tumors . and these ramifications can befelt under the skin (Fig. 369). The tumorconsists of a fibrous framework throughwhich run bundles of nerve-fibres, someof them completely medullated, othersonly partially so (Fig. 370). Large gan-glion-cells with characteristic nuclei andnucleoli are also sometimes found im-bedded in the tumor-mass. Waldenstrom,who doubts the correctness of Virchowsidea that a neuroma is composed largelyof nerve-fibres without medullary sheath,regards them as fibromata originating fromthe interstitial connective tissue. Westphal has traced neuromata of theskin to the endoneurium. The nerve-fibresin neurofibromata undergo a change whichis conceded by nearly all observers, in that the medullary sheath under-goes atrophy, and that the nerve-sheaths become the seat of hyalinedegeneration, which was first noticed and described by Schuster. Theenlargement of a nerve-end in amputation-neuroma is due to an abun-dant formation of small myelinic fibres produced from the neuroblasts. 369.—Portion of a neuroma fronthe right ear (after Bruns). 5i8 PATHOLOGY AND TREATMENT OF TUMORS. which have been exposed for a long time to irritation caused by cica-tricial tissue. It is well known that an amputation-neuroma will onlydevelop in connection with scar-tissue and the irritation incident to the
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Keywords: ., bookcentury1800, bookdecade1890, booksubjectneoplas, bookyear1895