. A new manual of surgery, civil and military. e action of the radio-active sub-stances, it would be folly to treat cancer solely by the latter. On the contrarythe patient must receive the best surgical treatment if the case is operable,and this must be augmented by radium and X-ray applications. Radiotherapy,therefore, is an adjunct of surgery- and the best results are obtained when itis combined with proper surgical treatment. The biologic action of mesothorium, radium and the Rontgen rays is identi-cal. The rays either stimulate the embryologic cell to mature into adult,differentiated cells


. A new manual of surgery, civil and military. e action of the radio-active sub-stances, it would be folly to treat cancer solely by the latter. On the contrarythe patient must receive the best surgical treatment if the case is operable,and this must be augmented by radium and X-ray applications. Radiotherapy,therefore, is an adjunct of surgery- and the best results are obtained when itis combined with proper surgical treatment. The biologic action of mesothorium, radium and the Rontgen rays is identi-cal. The rays either stimulate the embryologic cell to mature into adult,differentiated cells, or they destroy the cancer cells by producing a gigantism 634 SURGERY OF THE FEilALE PELVIS followed by a karrolysis and death of the celL At the same time the eoime.:tive tissue increases penetrating the cancer masses, which process is furtheraccompanied bv a marked leucocrtic cell infiltration. The therapeutic action of radium and mesothorium depends, 1st, on theamount and compactness of the substance used: 2nd, on the duration and *r^zn^. VaGI^.AI. The operation completed. The orifice Lraolt (a) closed by tying the sutures. The ■i (d).olaee. The vaginal concentration of the treatment and 3rd, on the filtering employed. The amountof radium or mesothorium necessary for a successful therapy should be atleast 25 mg. radium element. The mean amount recommended by most investi-gators is placed at 50 mg. radium element. It m important to determine themilligrams of radium element contained in the radium applicator. Fifty milli-grams of radium bromid contain mg. radium element: 50 me. radium SURGERY OF THE FEMALE PELVIS 635 chlorid contain mg. radium element; 50 mg. radium sulphate mg. radium element; and 50 mg. radium carbonate equal mg. radiumelement. Radium sulphate is insoluble in water and body fluids and hencebest suited for our purposes. If a radium container should accidentally breakor deteriorate while inserted in a patient the


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Keywords: ., bookcentury1900, bookdecade1910, bookpublishe, booksubjectsurgery