. A practical treatise on tumors of the mammary gland: . dvessels were more orless closely packed with young epithelial elements,through which their lumen was frequently diminishedor even obliterated. Even in those cases—and I haveexamined three—in which the skin covering the car-composed of sixteen glands. The history of the case may be found in thePhila. Med. Times, July 5, 1879, p. 484. * Arcliiv filr Gyncekohgie, Bd. viii, p. 181. Virchows Archil, Bd. xli, p. 485. ^ From a section of a nodule of the pectoral muscle, which I extirpated,along with an atrophying scirrhus, of fourteen years du


. A practical treatise on tumors of the mammary gland: . dvessels were more orless closely packed with young epithelial elements,through which their lumen was frequently diminishedor even obliterated. Even in those cases—and I haveexamined three—in which the skin covering the car-composed of sixteen glands. The history of the case may be found in thePhila. Med. Times, July 5, 1879, p. 484. * Arcliiv filr Gyncekohgie, Bd. viii, p. 181. Virchows Archil, Bd. xli, p. 485. ^ From a section of a nodule of the pectoral muscle, which I extirpated,along with an atrophying scirrhus, of fourteen years duration, and a denselyhard axillary glandular tumor, from a prolific married lady forty-five years ofage, on account of severe suffering. Her general health was excellent, and shestill menstruated. The macroscopic features of the tumor of the mamma arerepresented in fig. 29. CARCINOMA. 129 cinomatous mamma was pervaded by convex, elevatedridges, as large as crows quills, and whicli conveyedto the naked eye the idea of thrombosed lymphatics, Fio. Extension of Carcinoma into the Great Pectoral Muscle.—To the left of thefigure is seen a transverse section of an arteiy, the upper portion of thelymph sheath of which is infiltrated by epithelial cells. The alveoli be-tween the primary muscular fasciculi are due to the absorption or disap-pearance of the greater portion of the latter from the pressure exertedupon them by the accumulations of cells in the interfascicular connectivetissue. At several points the muscle corpuscles are seen to be more abun-dant than is normal, but this is an irritative phenomenon, and there is noevidence that they participate in the carcinomatous degeneration. The nu-clei of the cells alone are delineated. I have only found dilated lymphatics filled with coag-ulated lymph. The varieties of carcinoma are detennined by the9 130 VARIETIES. relative proportion of tlie stroma and cells, by certaindegenerations and transformations, and by tlie acci-den


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