. The endocrine organs; an introduction to the study of internal secretion . peration. Itwas, however, much higher than thison the third, fourth, and fifth days,averaging 266 Mere exposure ofthe pituitary was found to have nosuch effects. A case in man has beenrecorded by Simmonds in which therewas a malignant tumour of the parsnervosa extending to the pars inter-media, with marked diabetes insipidus (10 to 19 litres of urine per diem).This is probably a case of the cells of a malignant tumour assuming thefunctions of the tissues they are growing from (see p. 33). It has been found by Gus
. The endocrine organs; an introduction to the study of internal secretion . peration. Itwas, however, much higher than thison the third, fourth, and fifth days,averaging 266 Mere exposure ofthe pituitary was found to have nosuch effects. A case in man has beenrecorded by Simmonds in which therewas a malignant tumour of the parsnervosa extending to the pars inter-media, with marked diabetes insipidus (10 to 19 litres of urine per diem).This is probably a case of the cells of a malignant tumour assuming thefunctions of the tissues they are growing from (see p. 33). It has been found by Gushing that stimulation of the cervicalsympathetic or of its superior ganglion causes diuresis; he considers thisis brought about by provoking the secretion of the posterior lobe, sincestimulation of the superior cervical ganglion produces no effect if thepituitary be first removed. He therefore concludes that secreting nervespass through this ganglion to the pituitary. Gushing also states that ex-cision of the posterior lobe or separation of the stalk is sometimes followed. FIG. 71.—Young dog, eight months old. fourmonths after removal of the greater partof the pituitary body. (Gushing.) Noticethe tendency to adiposity, and the de-ficient development of the sexual organs. 104 The Endocrine Organs by prolonged polyuria: this may be caused by irritation of portions of parsintermedia which remain. According to Weed, Gushing, and Jacobson,puncture of the pituitary gives as definite results regarding glycosuria asBernards puncture of the fourth ventricle. In both cases there must be
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