Nervous and mental diseases . Fig. 154. —1, Normal anterior horn ; 2, anterior horn in a case of amyotrophic lateral sclerosis (Marie). it may appear earlier or later. It is somewhat more frequent in men thanin women. Direct inheritance is very rare, but a neuropathic tendencycan occasionally be traced. It has been noted as following variousalleged vague causes, such as anxiety, overwork, exposure to cold, con-cussion of the spine, syphilis, and various infectious and septicemic appearance years after an acute poliomyelitis has been already indicatedunder that caption. A close inqui
Nervous and mental diseases . Fig. 154. —1, Normal anterior horn ; 2, anterior horn in a case of amyotrophic lateral sclerosis (Marie). it may appear earlier or later. It is somewhat more frequent in men thanin women. Direct inheritance is very rare, but a neuropathic tendencycan occasionally be traced. It has been noted as following variousalleged vague causes, such as anxiety, overwork, exposure to cold, con-cussion of the spine, syphilis, and various infectious and septicemic appearance years after an acute poliomyelitis has been already indicatedunder that caption. A close inquiry will sometimes detect a history ofsymptoms antedating the alleged cause. There can be little doubt thatat least in some instances it is an expression of teratological defect in themotor and trophic portions of the central apparatus, and constitutes aprimordial shortcoming bv which these parts reach an earlv death. 26 402 DISEASES OF THE CORD PROPER. Morbid Anatomy.—The lesions of progressive spinal muscularatrophy embr
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