Lectures on localization in diseases of the brain, delivered at the Faculté de médecine, Paris, 1875 . voluminous branch of the Sylvian artery(see Fig. 37)—these lesions, I say, even when there is no par-ticipation of the central masses, produce in certain cases con-secutive sclerosis as marked as that which depends upon alesion of the anterior region of the internal capsule. Among these conditions there is one especially relating tothe location of cortical lesions, which should be made partic-ularly clear. We have observed that superficial softenings(yellow patches) occupying either the occ


Lectures on localization in diseases of the brain, delivered at the Faculté de médecine, Paris, 1875 . voluminous branch of the Sylvian artery(see Fig. 37)—these lesions, I say, even when there is no par-ticipation of the central masses, produce in certain cases con-secutive sclerosis as marked as that which depends upon alesion of the anterior region of the internal capsule. Among these conditions there is one especially relating tothe location of cortical lesions, which should be made partic-ularly clear. We have observed that superficial softenings(yellow patches) occupying either the occipital lobe, the pos- 124 DISEASES OF THE BRAIN. terior parts of the temporal or sphenoidal lobe, or the ante-rior regions of the frontal lobe, are not succeeded by consec-utive fascicular sclerosis, while on the other hand these scle-roses, as a rule, follow lesions of the two ascending convolu-tions (ascending parietal and ascending frontal), and the con-tiguous parts of the parietal and frontal lobes (Fig. 38). Fur-ther on I will return more especially to this point, which Inow merely Fig. 38.—Human brain, left side ; destruction of the ascending parietal convolu-tion and a great part of the ascending frontal convolution. Sth. In brief, the locality and extent of the lesion seemhere to be the two fundamental conditions ; the nature of thelesion seems to have no marked influence. The requiredlocality and extent being given, descending sclerosis shouldfollow, provided the lesion is a destructive one, that is, onecapable of interrupting the course of the medullar) of hemorrhage or softening, and simple or syphiliticencephalitis, have in this respect much the same rank. It isnot the same with certain tumors which, through a long periodof evolution, only crowd back or to one side the medul-lary elements without interrupting their continuity. This isthe reason why they may exist, even in the regions abovespecified, unaccompanied by consecutive fascic


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