. Annals of surgery . on-nective tissue grew nutand invaded a pocket ofthe stone. The lime saltsof the stone and the acidreaction of the urine withw h i c h the in\adingpedicle came in contactproduced metaplasia intohone with resultantosseous metamorphosis inthe calculus. No calcifi-cation was seen in theinvading connective tis-sue of these stones. Afterinfection and alkaliniza-tion of the pehic urine work in Case II there was secondarcalcium iilidsiihate. ).\alate stone I and theurine. Thev rew to a calcium carl)t)nate heingrelatively much it seems logi-cal to assume that thel


. Annals of surgery . on-nective tissue grew nutand invaded a pocket ofthe stone. The lime saltsof the stone and the acidreaction of the urine withw h i c h the in\adingpedicle came in contactproduced metaplasia intohone with resultantosseous metamorphosis inthe calculus. No calcifi-cation was seen in theinvading connective tis-sue of these stones. Afterinfection and alkaliniza-tion of the pehic urine work in Case II there was secondarcalcium iilidsiihate. ).\alate stone I and theurine. Thev rew to a calcium carl)t)nate heingrelatively much it seems logi-cal to assume that thelime salts are depositedfrom the lym])h or bloodin the portion of trans-plant bordering on thelumen, where nutritionalconditions are poorest,necrosis is greatest, andacidity increased by con-lact with the acid the bladder. Ossifi-cation follows as a se-([uence to the calcifica-tiiin, and is also aug-mented by the urine. The findings in stonesI and 2 suggest the fol-primary oxalate portionsize where thev became. Case II. High-power of base of stone, showing framc-i calcium deposits with invasion of bony trabecula (a). Stone formation, consisting mainly of248 OSSIFICATION IN KIDNEV STOXES The findings in stone 3 suggests a different process of development andto some extent contradict that given for the first two. The sacculation appa-rentlv occurred first, and calcification took place in a portion of the wall devoidof epithelium. Lime salts from the urine were then deposited on it in thenature of an incrustation, such as is seen upon a non-ahsorbable suture orother foreign body projecting into the urinary tract. A small amount ofossification took place in the base of the stone, where it joined the partiallycalcified jiedicle. Condition easily overlooked. I am indebted to Miss Mary E. Mavee of the Sprague Foundation,University of Chicago, for the chemical analyses of the stones. Strauss, Alfred A.: An Artificial Ureter Made from the .\bdomiiial Wall. Surg., Gyn


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Keywords: ., bookcentury1800, bookdecade1880, booksubjectsurgery, bookyear1885