. Tumours, innocent and malignant; their clinical characters and appropriate treatment. 1895demonstrated that the essential feature of the changedepends more on the epithelium than on the stroma of thevillus, for it undergoes irregular proliferation and assumesinvasive characters, penetrating the decidua and even themuscular wall of the uterus. The vessels of the villi dis-appear, the stroma degenerates, and the swollen conditionof the so-called vesicles is the result of cedema rather than of HYDATID HOLES 417 mucoid change. The mvasiveness or destructiveness of thesealtered villi has long bee


. Tumours, innocent and malignant; their clinical characters and appropriate treatment. 1895demonstrated that the essential feature of the changedepends more on the epithelium than on the stroma of thevillus, for it undergoes irregular proliferation and assumesinvasive characters, penetrating the decidua and even themuscular wall of the uterus. The vessels of the villi dis-appear, the stroma degenerates, and the swollen conditionof the so-called vesicles is the result of cedema rather than of HYDATID HOLES 417 mucoid change. The mvasiveness or destructiveness of thesealtered villi has long been recognized, and specimens havebeen observed in which the villi have perforated the uterusand caused fatal bleeding into the abdominal cavity. The hydatid mole (or chorion-ejnthelioma benignum) isnot common; it has been estimated by one writer (MadameBoivin, 1827j to occur once in 20,000 pregnancies, and byanother (Williamson, 1899) once in 2,400. It is quite certainthat only a small proportion of women who have expelledhydatid moles suffer from chorion-epithelioma, but no reliable. Fig. 205.—Microscopic appearance of a chorionic villus from a hydatid mole, intransverse section. estimates are available. The liability of a woman who hashad a miscarriage of this kind, to be the victim of sucha deadly disease as chorion-epithelioma malignum, rendersit advisable that she should keep under medical supervisionfor some months after such an event. Some writers are disposed to believe that there are twovarieties of the hydatidiform mole, one being purely innocent,the other giving rise to the malignant yet microscopical inquiries have not provided thesetheoretical distinctions with a histologic foundation. Relation of the hydatid mole (chorion-epitheliotna benignum)to lutein cysts.—Some valuable observations have been made2 B 418 GHOBION-EPITHELIOMA on the frequent association of bilateral lutein cysts of theovary and the so-called hydatid mole; indeed, the pr


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Keywords: ., bookcentury1900, bookdecade1910, booksubjectneoplasms, bookyear19