. The American journal of the medical sciences. short osteophytic vegetations,which are inseparably connected with the compact tissue of the femur, andrepresent a true hyperplastic process. Again, the ossified portion of thegrowth may form a huge mass of what looks like spongy bone, as in , of the humerus. In other examples, the appearances are those ofdense ivory-like bone, or, asis illustrated by Nos. 198 ofthe humerus and 1609 of thetibia, the latter of which isreproduced in Fig. 8, the tu-mour is principally composedof a collection of large tubersor nodules, which are asfragile as dr
. The American journal of the medical sciences. short osteophytic vegetations,which are inseparably connected with the compact tissue of the femur, andrepresent a true hyperplastic process. Again, the ossified portion of thegrowth may form a huge mass of what looks like spongy bone, as in , of the humerus. In other examples, the appearances are those ofdense ivory-like bone, or, asis illustrated by Nos. 198 ofthe humerus and 1609 of thetibia, the latter of which isreproduced in Fig. 8, the tu-mour is principally composedof a collection of large tubersor nodules, which are asfragile as dried mortar. In the majority of in-stances, the intercellular sub-stance is simply calcified orpetrified, so that the cellularelements are clearly displayedon the addition of chlorohy-dric acid. In others, or inparts of the same specimen,the tumour is pervaded byimperfect bone. Hence,Grohe divides osteoid sar-comas into spongoid and ossi-fying sarcomas; the formerbeing characterized by calca-reous infiltration, and thelatter by the formation of. Op. cit., vol. ii. p. 375. Bardlebens Lehrbuch der Chir., etc., 6th ed., vol, i. p, 580. 870 Gross, Sarcoma of the Long Bones. [Oct. new bone. Such a distinction, however, is entirely superfluous, since cal-cification is the initial stage of ossification, and the clinical features andprognosis of both forms are identical, although Cornil and Ranvier^ erro-neously state that ossifying sarcomas are benign affections, while calcifyingsarcomas are to be regarded with suspicion. As happens in the other A-arieties of periosteal sarcomas, the bone uponor around which the tumour grows is usually not involved in the disease,but in about 40 per cent, of all cases the subjacent medullary canal orspongy substance of the epiphysis is the seat of similar deposits. Insome instances the internal and external tumours communicate by anopening in the compact tissue of the bone; but, as a rule, the latter re-mains entire, although it is sometimes the seat o
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