A treatise on the principles and practice of medicine . come curved; the teeth may becomepeg-like or the notches grind off even. The other associates of Hutchin-sons triad—deafness and the ground-glass cornea—are discussed onpages 214 and 216. Blue sclerotics are accounted symptomatic of con-genital lues, and Heine found optic neuritis in 82 per cent. The Wasser-mann test is positive in 90 to ICO per cent.; it may be absent at first, toappear as the clinical signs develop; in one series it was positive in 298out of 300 cases. Bones.—As in adults, there may be periostitis, tophi or perforatedpa
A treatise on the principles and practice of medicine . come curved; the teeth may becomepeg-like or the notches grind off even. The other associates of Hutchin-sons triad—deafness and the ground-glass cornea—are discussed onpages 214 and 216. Blue sclerotics are accounted symptomatic of con-genital lues, and Heine found optic neuritis in 82 per cent. The Wasser-mann test is positive in 90 to ICO per cent.; it may be absent at first, toappear as the clinical signs develop; in one series it was positive in 298out of 300 cases. Bones.—As in adults, there may be periostitis, tophi or perforatedpalate. Osteochondritis occurs especially in the lower end of the femur;the diaphysis and epiphysis may be separated. There is (a) overgrowthof the cartilage of the diaphysis which produces the wavy line of whitecartilage cells; (b) the line of cartilage cells becomes thick and fociof decalcification occur; (c) the cartilage is as prominent as in rickets,the part nearest the bone being soft. The immobility of the leg maysuggest paralysis (Parrot).. Fig. 14.—Notched teeth. Malformation of permanent teeth found in hereditary syphilis. (Jonathan Hutchinson.) Viscera.—Diffuse infiltration is much more frequent than are characteristic changes in certain organs which are rarelyinvolved in acquired syphilis, e. g., in the thymus, umbilical cord,pancreas, lungs, intestines and adrenals. The liver and spleen are greatlyenlarged; the Spirochete pallida is found in these viscera in vast numbers,even in the macerated fetus. To conserve the classification, these changeshave been described under Special Symptomatology. Fournier de-scribes enlargement of the peripheral veins. Vascular changes areespecially marked, as in the umbilical vessels, with a tendency to hemor-rhage—syphilis hemorrhagica neonatorum. Hemorrhages in the skin,mucous membranes and viscera, may be profuse, especially in the liverand lungs, where the circulation is precipitately altered after
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