American journal of pharmacy . Cocaine-chloro-aurate, x ioo. POTASSIUM lEKM ANGANATE TEST/ To y> of a 2 per cent, solution of cocaine are added fivedrops of permanganate test solution. A precipitate is formed con-sisting of violet-red, rectangular plates. The other common alka-loids either immediately or slowly reduce the permanganate withoutforming crystalline This is also true of the cocainesubstitutes, holocaine, acoine, and euphthalmine, which almost in- F. Giesel, Phartn. Zeit., 1886, p. , Comm. Org. Anal. 2d Ed., vol. m, pt. ii, p. 144. 198 Identification
American journal of pharmacy . Cocaine-chloro-aurate, x ioo. POTASSIUM lEKM ANGANATE TEST/ To y> of a 2 per cent, solution of cocaine are added fivedrops of permanganate test solution. A precipitate is formed con-sisting of violet-red, rectangular plates. The other common alka-loids either immediately or slowly reduce the permanganate withoutforming crystalline This is also true of the cocainesubstitutes, holocaine, acoine, and euphthalmine, which almost in- F. Giesel, Phartn. Zeit., 1886, p. , Comm. Org. Anal. 2d Ed., vol. m, pt. ii, p. 144. 198 Identification of Cocaine. (Am. Jour. May, 1911. stantly reduce the permanganate. Alpha- and beta-eucaine andstovaine do not reduce the permanganate immediately, resemblingcocaine in this respect. No crystals, however, are formed in thesecases. The permanganate reaction requires a fairly concentrated solu-tion of cocaine, but there is no difficulty in obtaining the character- Fig. Cocaine permanganate, x 100. istic violet-red plates in a 2 per cent, solution. With a oneper cent, solution, the crystals (of cocaine permanganate) onlyform as evaporation takes place. 4 PLATINUM CHLORIDE To j4 of a one per cent, solution of cocaine are addedtwo drops of platinum chloride test solution. The test tube shouldnot be shaken, as larger and better formed crystals will result * Allen, Comm. Org. Anal. 2d Ed., vol. HI, pt. ii, p. B. Lyons, Am. Jour. Pharmacy, lvii, No. 10. Am•M^ir-19narm-} Identification of Cocaine. 199 when the solution is undisturbed. A buff colored precipitate isformed which, under the microscope, appears as large feathers orplumes, sometimes arranged in stellate pattern. In higher dilutions(1:600) crystals slowly form which resemble carpet Alpha-eucaine, with the above test, gives bundles of fine needles;beta-eucaine, after 30 minutes, gives a few very large, broad leaves,rosettes and cubes; holocaine gives small stars; acoi
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Keywords: ., bookcentury1800, bookdecade182, booksubjectpharmacy, bookyear1829
