Practical physiological chemistry; a book designed for use in courses in practical physiological chemistry in schools of medicine and of science . output of moist feces,calculated on the basis of data secured from the examination of over1000 stools, was about 100 grams. The variation in the normal dailyoutput being so great renders this factor of very little value for diag-nostic purposes, except where the composition of the diet is accuratelyknown. Lesions of the digestive tract, a defective absorptive function,or increased peristalsis as well as an admixture of mucus, pus, blood,and patholog
Practical physiological chemistry; a book designed for use in courses in practical physiological chemistry in schools of medicine and of science . output of moist feces,calculated on the basis of data secured from the examination of over1000 stools, was about 100 grams. The variation in the normal dailyoutput being so great renders this factor of very little value for diag-nostic purposes, except where the composition of the diet is accuratelyknown. Lesions of the digestive tract, a defective absorptive function,or increased peristalsis as well as an admixture of mucus, pus, blood,and pathological products of the intestinal wall may cause the totalamount of excrement to be markedly increased. An idea of the varia-tion of the percentage of dry matter in the feces evacuated after theingestion of different diets may be gathered from a consideration of thefollowing table.^ Schmidt & Strasburger: Die Fazes des Menschen, Berlin iqi5 221 222 PHYSIOLOGICAL CHEMISTRY INFLUENCE OF DIET ON FECAL DRY MATTER Diet Dry Matter Percent. Nursing [ Adult. Meat Bread . The fecal pigment of the normal adult is hydrobilirubin This,pigment originates from the bilirubin which is secreted into the intes-tine in the bile, the transformation from bilirubin to hydrobilirubinbeing brought about through the activity of certain bacteria. Hydro-bilirubin is sometimes called stercobilinand bears a close resemblance to urobilinor may even be identical with that pig-ment. Neither bilirubin nor biliverdinoccurs normally in the fecal discharge ofadults, although the former may be de-tected in the excrement of nursing in-fants. If these pigments are found inthe feces of adults, they indicate anabnormally rapid transit through thelarge bowel thus preventing their trans-formation into hydrobilirubin. Fre-quently, in some way as yet unknown,probably through the agency of certain bacterial processes, color-less hydrobilirubinogen (
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