. Anatomischer Anzeiger. Anatomy, Comparative; Anatomy, Comparative. 15. to Dr. J. L. Crenshaw of Charlottesville, Va. The specimen was removed from the uterus immediately after hysterectomy and sent to me in a 5 7o formalin solution. The chorionic vesicle had been opened but the amnion and yolk sac were left intact (Fig. 1). The specimen was transferred to 95 % alcohol after several hours. Both embryo and sac were stained in toto with borax carmine, im- bedded in paraffine and sectioned at 10 microns. The stain proved rather faint and some of the slides were placed for several seconds in a sa
. Anatomischer Anzeiger. Anatomy, Comparative; Anatomy, Comparative. 15. to Dr. J. L. Crenshaw of Charlottesville, Va. The specimen was removed from the uterus immediately after hysterectomy and sent to me in a 5 7o formalin solution. The chorionic vesicle had been opened but the amnion and yolk sac were left intact (Fig. 1). The specimen was transferred to 95 % alcohol after several hours. Both embryo and sac were stained in toto with borax carmine, im- bedded in paraffine and sectioned at 10 microns. The stain proved rather faint and some of the slides were placed for several seconds in a saturated aqueous solution of saffranin. This yielded a very satis- factory differential stain. Microscopic study revealed a very excellent state of preservation of the entire specimen including the chorionic villi. Comparisons will be made with the structure of the umbilical vesicle of a 9,2 mm human embryo, previously described (24), and several of the illustrations are from this specimen. The umbilical vesicle of this younger embryo was at the height of its development. The changes consequent upon a slight increase in age as seen in the older specimen are instructive. Part I. Macroscopic Appearance and Comparisons. The umbilical vesicle has an almost spheric form, but is drawn out into a slender tube at its proximal pole where it passes into the pedicle. It thus has roughly the pyriform shape as ordinarily described. The surface of the vesicle is slightly roughened due to the tubules and blood-vessels in the outer surface of the wall. Its dimensions are 6 mm X 4 mm, an increase of 1 mm in both axes over that of the 9,2 mm embryo. This indicates growth for at least a week beyond the first month (30 days). Meyer's (33) figures given for 18 vesicles in the collection of Dr. Mall of John Hopkins University show con- siderable variation in size among the umbilical vesicles of embryo Fig. 1. Photograph of 13 mm human em- bryo, showing amnion, umbilical vesicle and open chorionic ves
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Keywords: ., bookcentury1900, bookdecade1910, bookpublisherjenag, bookyear1910