American journal of physiology . mals made by W. T. Porter theaverage depressor fall was 33 per cent. ^ W. T. Porter: This journal, 1907, xx, p. 403. State of the Vasomotor Centre in Diphtheria Intoxication 439 protocol of the first of these experiments, given on page 436, clearlyindicates that the rabbit, flaccid and insensible, was about todie. In the experiment of January 20, systemic death had actuallytaken place, the respiration had ceased beyond recall, the heart hadstopped, the arteries were empty, but the vasomotor cells werestill intact and the heart was made to beat again long enough
American journal of physiology . mals made by W. T. Porter theaverage depressor fall was 33 per cent. ^ W. T. Porter: This journal, 1907, xx, p. 403. State of the Vasomotor Centre in Diphtheria Intoxication 439 protocol of the first of these experiments, given on page 436, clearlyindicates that the rabbit, flaccid and insensible, was about todie. In the experiment of January 20, systemic death had actuallytaken place, the respiration had ceased beyond recall, the heart hadstopped, the arteries were empty, but the vasomotor cells werestill intact and the heart was made to beat again long enoughfor the vasomotor reflex to be measured. Following is the pro-tocol. Experiment January 20, 1914. — A rabbit weighing 1400 gramsreceived in the ear vein .004 diphtheria toxin at ,January 18. The morning of January 20 the rabbit seemedlistless. It was placed on a table and observed continuouslyfrom 9 As the day wore on, the rabbit could not hold upthe head, nor regain his feet when laid upon one side. Finally,. Figure 1. From an animal dead of diphtheria toxin, but with surviving vasomotorcells and resuscitated circulation. The upper line shows carotid blood pressurerecorded with a membrane manometer. The graduation scale in mm. Hg is seenat the left. The middle line records the atmospheric pressure and the stimulationof the depressor nerve. The lower line gives time in 5-second intervals. about , he lay prone, the head stretched on the table,and the respiration feeble and labored. At he seemed sonear death, that he was placed on the operating board. Deathat once followed; there was no corneal reflex, no respiration, noheart beat, the carotid artery seemed empty, and the rectaltemperature was 32° C. The rabbit was completely was quickly tracheotomized and artificial respiration wasestablished. Warm normal saline solution was injected into theexternal jugular vein. The heart began to beat, though feebly,scarcely raising the writin
Size: 2959px × 844px
Photo credit: © The Reading Room / Alamy / Afripics
License: Licensed
Model Released: No
Keywords: ., bookautho, bookcentury1800, bookdecade1890, booksubjectphysiology
