. The Journal of immunology . \j V. Chart 1a. Weight ChartJuly 23, 1913. Both guinea pigs received tubercle bacilli suspension, x Indi-cates date of injection with typhoid vaccine (5,000,000 typhoid bacilli). 285 286 HELEN BALDWIN AND ELISE S. leSPERANCE pigs were made in the Herter Laboratory. The followingobservations which make up the major part of the work were. T. B. 3 Gu/NB/^ p/ss T. B. -f- VAcc/fVE 6 Guinea p/gs \AOV Chart IIa. Average WeightsOn October 21, 1913, nine guinea pigs were injected with 6 mgm. tuberclebacilli suspension, x Indicates the date of injection with 5,000,000 typho


. The Journal of immunology . \j V. Chart 1a. Weight ChartJuly 23, 1913. Both guinea pigs received tubercle bacilli suspension, x Indi-cates date of injection with typhoid vaccine (5,000,000 typhoid bacilli). 285 286 HELEN BALDWIN AND ELISE S. leSPERANCE pigs were made in the Herter Laboratory. The followingobservations which make up the major part of the work were. T. B. 3 Gu/NB/^ p/ss T. B. -f- VAcc/fVE 6 Guinea p/gs \AOV Chart IIa. Average WeightsOn October 21, 1913, nine guinea pigs were injected with 6 mgm. tuberclebacilli suspension, x Indicates the date of injection with 5,000,000 typhoidbacilli (vaccine). made in the Department of Pathology at Cornell UniversityMedical College. This later series, which was suggested by the results of the INFLUENCE OF TYPHOID VACCINE 287 early work at the Herter Laboratory was divided into 2 experi-ments : 1. To determine the effect of typhoid vaccine on large groupsof tuberculous guinea-pigs with active lesions. 2. To determine the effect, if any, of typhoid immunizationon the susceptibility of guinea-pigs to inoculation with virulenttubercle bacilli; , immunizing the animals to typhoid andinoculating them later with tubercle suspension. 430420 •: - S : S ?•-•e2SS-*=ssS?=- -- 5 /i *to / .• 4O0 / / ^ /l soo / /v/ ^/ \ 380 J / \ -^v.^^^^ ^ 370 f / A^ A \ 360 /f\ V/ \ \ J50 *? / \ i^-^ 340 If


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