The Journal of laboratory and clinical medicine . xternal surface was smooth but gave one the feeHng of shght ele-vations and shallow depressions as the fingers were passed over the cut section there were presented multiple lobulations, varying in size fromthat of a pin head to that of the little finger nail, varying in shade of color butin no way yellowish to indicate jaundice or green to indicate extravasation ofbile. These lobulations were somewhat oval in shape and were separated fromeach other by strands of connective tissue varjqng in amount. The gall bladdershowed no signs


The Journal of laboratory and clinical medicine . xternal surface was smooth but gave one the feeHng of shght ele-vations and shallow depressions as the fingers were passed over the cut section there were presented multiple lobulations, varying in size fromthat of a pin head to that of the little finger nail, varying in shade of color butin no way yellowish to indicate jaundice or green to indicate extravasation ofbile. These lobulations were somewhat oval in shape and were separated fromeach other by strands of connective tissue varjqng in amount. The gall bladdershowed no signs of disorder and there were no stones in the ducts. (See Fig. 2.)The sections for microscopical examination were stained with hematin andeosin and toluidin blue. The most striking feature was the preservation of livercells in certain areas, with the sudden appearance of degenerated areas, large inarea compared to the normal liver cell areas, and in which fatty degenerationwas prominent. Then, again, the appearance around these areas of connective. Fig- 2.—M. H. Cut section, showing tlie whole liver to he cirrhosed. The cirrhosis is multilobular, withoutbeing bile-stained and divided by connective-tissue hyperplasia. tissue hyperplasia, varying in breadth and degree of fibroblastic activity with amoderate infiltration of round cells. Some of the sections indicated by thescarcity of round cells and the relatively few elongated nuclei of the fibroblastsundoubtedly were older processes. In these connective strands were occasionallyseen groups of nuclei, arranged in somewhat parallel rows which might indicatenew bile capillaries or hypertrophic bile ducts. In some places the strands ofconnective tissue appeared to invade the lobule and separate the liver cells intocolumns. There appeared also in certain portions, to be a connection betweenthese so-called new bile capillaries and a column of liver cells. It has been sug-gested that they might be liver cells reverting to their primit


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Keywords: ., bookcentury1900, bookdecade1910, booksubject, booksubjectmedicine