Journal and proceedings of the Royal Society of New South Wales . COOH group OHinto ,CH3 group was confirmed by treating the acidwith alkaline bromine liquor for one day at 0° 0., when themethyl group was split off as bromoform. After removalof this latter body, and acidifying with sulphurous andsulphuric acids, an acid was obtained, which on recrystal-lisation from hydrochloric acid melted at 94 â 95° showed it to be dibasic, and its identity witha-isopropyl-glutaric acid was confirmed by the preparationof the anhydride melting at 53-54° C. This acid was alsopresent in the
Journal and proceedings of the Royal Society of New South Wales . COOH group OHinto ,CH3 group was confirmed by treating the acidwith alkaline bromine liquor for one day at 0° 0., when themethyl group was split off as bromoform. After removalof this latter body, and acidifying with sulphurous andsulphuric acids, an acid was obtained, which on recrystal-lisation from hydrochloric acid melted at 94 â 95° showed it to be dibasic, and its identity witha-isopropyl-glutaric acid was confirmed by the preparationof the anhydride melting at 53-54° C. This acid was alsopresent in the liquid acids produced by the oxidation ofpiperitone by means of alkaline potassium permanganatesolution. POSITION OF THE DOUBLE LINKAGE IN PIPERITONE, PART II. 43 On combustion the following results were obtained, viz:0*1270 gram gave 0*2580 gram C02, and 0*0932 gram Calculated for OeHi404 Carbon 55*24% 55*17% Hydrogen 8*15 8*04 The generic relation between piperitone and the acidsdescribed is shown graphically, as follows, viz:âCH3 CH3 CH3 I. CâOH I c=o COOH COOH H2C COOH H8C HoC / COOH H2C COOH CH CH / \H3C CH3 a-hydroxy-a-methyla-isopropyl adipic acid. CH ICH / \H3C CH3 a-isop ropy 1-y-acety 1-butyric acid. CH CH / \H3C CHS a-isopropyl-glutaric acid. Piperitonehydroxylamino oxime.âMost of the publishedmethods for the preparation of this substance require heat-ing of the solutions, but the best method, in the authorsopinion, particularly if using the highly active ketone, i&the procedure usually adopted for the preparation ofcarvoxime, viz:â Five grams of ketone in 25 ccs. alcohol and 5 gramshydroxylamine hydrochloride in 5 ccs. water, when coldtare mixed with a solution of 5 grams caustic potash in 5 ccs~water, also cold, and allowed to stand overnight. Withina few hours the whole solidifies to a solid mass. On wash-ing with water, and recrystallising from alcohol and aceticether a quantitative yield is obtained. 44 MAX HENRY. THE INCIDENCE OF
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Keywords: ., bookcentury1800, bookdecade1860, booksubjectscience, bookyear1867
