Enzyme catalysing DNA recombination. Molecular model of the enzyme CRE (cyclization recombination) recombinase (blue and green) mediating the recombin


Enzyme catalysing DNA recombination. Molecular model of the enzyme CRE (cyclization recombination) recombinase (blue and green) mediating the recombination of strands of DNA (deoxyribonucleic acid, purple) at a Holliday Junction. This recombination is a natural genetic process known as crossing over, and involves the mixing of two strands of DNA. Recombinase enzymes snip open each DNA strand, starting the process going and forming a four-way alignment known as a Holliday Junction. It is this structure that other recombinases, like CRE, attach to as they continue the process.


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Photo credit: © LAGUNA DESIGN/SCIENCE PHOTO LIBRARY / Alamy / Afripics
License: Licensed
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