. A Reference handbook of the medical sciences : embracing the entire range of scientific and practical medicine and allied science. Fig. 4122. pushing them aside and destroying them by pressure,maintaining, meanwhile, its own integrity. A tubercle,under the same conditions, seems not so much to overrunthe tissue by crowding, but to lead to degeneration ofthe tissues among which it comes, itself also promptlydegenerating. Even with this low power several tubes,evidenced by the darker, shaded streaks at the upper andlower portions, can be seen in the midst of the gumma. Fig. 4123 is taken from


. A Reference handbook of the medical sciences : embracing the entire range of scientific and practical medicine and allied science. Fig. 4122. pushing them aside and destroying them by pressure,maintaining, meanwhile, its own integrity. A tubercle,under the same conditions, seems not so much to overrunthe tissue by crowding, but to lead to degeneration ofthe tissues among which it comes, itself also promptlydegenerating. Even with this low power several tubes,evidenced by the darker, shaded streaks at the upper andlower portions, can be seen in the midst of the gumma. Fig. 4123 is taken from the same gumma, photo-graphed with the quarter-inch objective, near its right. Fig. 4123. lower border ; on that side of the picture are seen severalof the tubes, compressed and pushed aside, but maintain-ing their integrity. The structure, which can be madeout with ease, is composed of comparatively scanty small,rounded nuclei, placed in a nearly clear hyaline basis sub-stance of indistinctly fibrillar connective tissue ; in the midst of this are seen many spindle-shaped cells ; manyof these cellular elements are the remains of the pre-existing tissues, which have been displaced by the newformation. These cells are not placed haphazard, butare arranged somewhat in concentric whorls, or else fol-low waving courses of short extent. It suggests the de-velopment of the gumma from several points, the growthsfrom which coalesce to form a single deposit, and it re-minds one strongly of the mode of growth of a fibroma,but the actual centres of growth seen in the latter arewanting in the gumma ; in the gumma the cells of roundand spindle forms are distributed impartiall


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Keywords: ., bookcentury1800, bookdecade1880, booksubjectmedicine, bookyear188