. General surgical pathology and therapeutics, in fifty lectures : a textbook for students and physicians. Connective-tissue infiltration advancing into the cutis from the borders of a cancerous noduleof the mamma; the dark shadings correspond to the advanciug small-celled 50 diameters. The extension of this infiltration into the fatty tissue occurs justas in inflammation ; most of the young cells are found in the vicinityof the vessels, so that we can scarcely avoid thinking that in thesecases also white blood-cells escaping from the vessels cause the cellu-lar infiltra
. General surgical pathology and therapeutics, in fifty lectures : a textbook for students and physicians. Connective-tissue infiltration advancing into the cutis from the borders of a cancerous noduleof the mamma; the dark shadings correspond to the advanciug small-celled 50 diameters. The extension of this infiltration into the fatty tissue occurs justas in inflammation ; most of the young cells are found in the vicinityof the vessels, so that we can scarcely avoid thinking that in thesecases also white blood-cells escaping from the vessels cause the cellu-lar infiltration. As in these cases the infiltration of the connective tissue with44 672 TUMORS. lymphoid cells is very decidedly the predominant morbid process,while the epithelial proliferation is very secondary, I formerly tried togive this form of cancer of the breast the name of connective-tissuecancer. But, as this has led to misinterpretation in regard to themodern anatomical understanding of carcinoma, I shall not try topreserve this term. Fig. Cellular infiltration of the fatty tissue in the periphery of a hard cancer of the hreast; the blood-vessels injected. Magnified 200 diameters. The peculiar anatomical and clinical course has caused some sur-geons to strike this new formation from the list of tumors, and par-ticularly from that of cancers. If we examine more closely the clinicalcourse of these cases, we have already noticed that they usually onlyoccur in old persons, and that the local disease progresses slowly;some cases last seven or eight years before half of one breast is atro-phied. The general health meantime remains unimpaired. Thelymphatic glands occasionally participate in the disease ; in this casethe process goes on just as in the mamma ; there is very little enlarge-ment, but much hardening and cicatricial shrinking. The more rap-idly and completely the new formation atrophies, and the more slowlythe process extends, the more injurious it is; after extirpat
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Keywords: ., bookcentury1800, bookdecade1870, booksubjecttherapeutics, bookyea
