. A Reference handbook of the medical sciences embracing the entire range of scientific and practical medicine and allied science . ou may involve the periglandular structures andgive rise to dense connectixe-tissue masses about thenode. Such nodes are of course functionless. Atrophy. The Ijmph nodes of children are larger thanthose of atlults, so that a slight atrophy of these struct-ures takes place during life. In old age a more com-plete atrophy, with a diminution in the number of lymph-ocytes and thickening of tlie fibrous tissue of the node,is a regular occurrence. The node may be reduce
. A Reference handbook of the medical sciences embracing the entire range of scientific and practical medicine and allied science . ou may involve the periglandular structures andgive rise to dense connectixe-tissue masses about thenode. Such nodes are of course functionless. Atrophy. The Ijmph nodes of children are larger thanthose of atlults, so that a slight atrophy of these struct-ures takes place during life. In old age a more com-plete atrophy, with a diminution in the number of lymph-ocytes and thickening of tlie fibrous tissue of the node,is a regular occurrence. The node may be reduced toa mere shell, the centre of which is filled with fat tissue;or it may be small and hard and the fat tissue lie aboutit. Such nodes are paler than normal owing to the in-crease in the amount of connective tissue and to a dimi-nution in the blood supply. Amyloid degeneratioH of the reticulum and of the wallsof the blood-vessels may appear in the lymph nodes as apart of a general amyloid degeneration of the organs ofthe following prolonged suppuration, tuberculosis,or syphilis, or it may be limited to the nodes. In the. ^n^S, i.*! •*.*?. ^?r. • ^oih-- c Fib. 3312.—Piprmentation of Lymph Node, with Chronic Inflamma-tion, a, Capsule; h, follicle; c. dilated .sinus mth phagocytescarrying pigment. (Dr. F. C. Wood.) latter case, amyloid degeneration is most frequently seenin the hyperplastic nodes of pseudoleukainia, and inchronic or tuberculous inflammation. In advanced casesthe fibres of the reticulum may become greatly swollenso as to cause the parenchyma of the node to undergoatrophy. Under such circumstances the node is hard and transparent and gives a mahogany brown when treatedwith tincture of iodine. Sections stained with methylviolet or thionin show the metachromatic staining char-acteristic of amyloid in the other portions of the body. Iljiiiliiii (hljriiij-atiijii of the Avails of the vessels and thereticulum is occasionally seen in tuberculous or carcinom-at
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