Venoms; venomous animals and antivenomous serum-therapeutics . d the skin, which is distended to allow it topass. Towards the base of the spine, the edges of the cannelure areunited, and form a hollow, bony cone, the walls of which are linedwith the cells that secrete the toxic fluid. Greater Weevers areusually from 12 to 30 cm. inlength, and of a reddish oryellowish-grey colour, withblue or violet spots. Theyare caught in trawls and arefairly common on sandybottoms. In the month ofJune they approach the shorefor the purpose of venom of the Weeverhas formed the subject ofinteresti


Venoms; venomous animals and antivenomous serum-therapeutics . d the skin, which is distended to allow it topass. Towards the base of the spine, the edges of the cannelure areunited, and form a hollow, bony cone, the walls of which are linedwith the cells that secrete the toxic fluid. Greater Weevers areusually from 12 to 30 cm. inlength, and of a reddish oryellowish-grey colour, withblue or violet spots. Theyare caught in trawls and arefairly common on sandybottoms. In the month ofJune they approach the shorefor the purpose of venom of the Weeverhas formed the subject ofinteresting studies by Giin-ther, Gressin,^ Bottard,Phisalix,- and more recentlyby Kobert^ and A. Briot.* In order to procure suffi-cient quantities of it for ex-perimental purposes, Briotcuts off the venomous spines and the surrou7iding tissue with a pairof scissors ; he then pounds the whole in a mortar, and mixes thepulp with pure glycerine. After filtration through paper, a toxicsolution is obtained, which does not deteriorate by keeping, and isneutral to Fig. 108.—A, Operculum and opercular spineof the Lesser Weever {Trachiniis vipera) ; ar,articular surface of the operculum ; c. op, borlyof the opercular spine; c. an, canal of thespine ; z, space occupied by the , Spine belonging to the first dorsal fin ; c. an,efferent poison-canal in the spine. Thhe Paris, 1884. - Bulletin dio Museum dhistoire naturelle, 1899. ^ Giftfische unci Fischgifte, Vortrdge im BostocJcer Fischerverein, 1902, andDie tnedizinische WochenscJiriff, 1902. ^ Comytes rendus de la Societe de Biologie, October 25 and November 8, 1902,and June 21, 1904 ; Journal de Physiologic^ March, 1903. VENOMS IN THE ANIMAL SERIES 299 A few drops of this liquid are sufficient to kill guinea-pigs, which,immediately after receiving an injection in the thigh, exhibit paralysisof the leg with tetanic convulsions; twenty-four hours later aneschar is formed, and death supervenes on the second or third day. T


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