Beta secretase enzyme interacting with a membrane, molecular model. The enzyme (white ribbons) with an inhibitor molecule (coloured, see C015/1977) is
Beta secretase enzyme interacting with a membrane, molecular model. The enzyme (white ribbons) with an inhibitor molecule (coloured, see C015/1977) is above the membrane (yellow and grey, across bottom). This enzyme, of the type known as aspartic-acid protease, is also known as beta-site amyloid precursor protein cleaving enzyme 1 (BACE-1). It is a transmembrane protein that is thought to play a role in Alzheimer's disease through the build up of amyloid plaques in the brain. Drugs that inhibit this enzyme may help slow the progress of the disease.
Size: 3650px × 4831px
Photo credit: © RAMON ANDRADE 3DCIENCIA/SCIENCE PHOTO LIBRARY / Alamy / Afripics
License: Licensed
Model Released: No
Keywords: 1, 2, alzheimers, amyloid, app, artwork, asp2, aspartic, aspartyl, bace, bace1, background, beta, beta-secretase, beta-site, binding, biochemical, biochemistry, biology, biomolecule, brain, cell, cleaving, complex, cut, cut-, cut-outs, cutout, cutouts, disease, drug, enzyme, graphic, illustration, inhibiting, inhibitor, interacting, macromolecule, medical, medicine, memapsin, memapsin-2, membrane, membrane-, model, molecular, molecule, neurological, neurology, outs, plaques, precursor, protease, protein, proteomics, ribbons, secondary, secretase, structure, transmembrane, white