. Ciba Foundation symposium on drug resistance in micro-organisms: mechanisms of development. Drug resistance in microorganisms. 222 P. P. Slonimski and H. de Robichon-Szulmajster individual purine and pyrimidine bases is even more striking (Table VIII). Here again we find the same situation as in the mutation study: adenine is the most effective of all the bases studied and thymine is slightly more effective than uracil. Adenine and cofactor E act synergistically while cofactor T is inhibitory. Substances assayed for stimulation and found 100 ?o» .jO co-fT E 9'. CONTROL ^CO-F T HRS Fig. 3. Ef
. Ciba Foundation symposium on drug resistance in micro-organisms: mechanisms of development. Drug resistance in microorganisms. 222 P. P. Slonimski and H. de Robichon-Szulmajster individual purine and pyrimidine bases is even more striking (Table VIII). Here again we find the same situation as in the mutation study: adenine is the most effective of all the bases studied and thymine is slightly more effective than uracil. Adenine and cofactor E act synergistically while cofactor T is inhibitory. Substances assayed for stimulation and found 100 ?o» .jO co-fT E 9'. CONTROL ^CO-F T HRS Fig. 3. Effect of commercial erythrose (0-5 ) or threose (1 ) on respiratory adaptation. Adaptation in aerated phosphate buffer con- taining 15 mg. glucose/ml. inactive are the following: D-glucose, D-ribose, 2-deoxy-D-ri- bose, D-arabinose, L-arabinose, D-xylose, L-fucose, L-rham- nose, D-erythrose, L-erythrose, L-erythritol, L-threose formate, glycerol, ethanol, gluconic acid lactone, i-tartaric acid, furfural, furfuryl alcohol, meso-inositol, ergosterol, tween 80, yeast extract (Difco), casein hydrolysate (enzymic), vitamin Bi25 folic acid, haemin, haematoporphyrin, mixture of trace Please note that these images are extracted from scanned page images that may have been digitally enhanced for readability - coloration and appearance of these illustrations may not perfectly resemble the original Ciba Foundation; Wolstenholme, G. E. W. (Gordon Ethelbert Ward); O'Connor, Cecilia M. (Cecilia Mary), 1927-. Boston, Little, Brown
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