. Manual of bacteriology. Bacteriology. 198 INFLAMxMATORY AND SUPPURATIVE CONDITIONS. =^- conditions elsewhere, in osteomyelitis, in septic inflamma- tions of the urinary passages, in pyaemia and septicasmia, in the course of or following infective fevers, and not very infrequently as a sequel to acute pneumonia. In some cases, especially when the valves have been previously diseased, the source of the infection is quite obscure. It is evident that as the vege- tations are composed for the most part of unorganised mate^ rial, they do not offer the same resistance to the growth of bacteri
. Manual of bacteriology. Bacteriology. 198 INFLAMxMATORY AND SUPPURATIVE CONDITIONS. =^- conditions elsewhere, in osteomyelitis, in septic inflamma- tions of the urinary passages, in pyaemia and septicasmia, in the course of or following infective fevers, and not very infrequently as a sequel to acute pneumonia. In some cases, especially when the valves have been previously diseased, the source of the infection is quite obscure. It is evident that as the vege- tations are composed for the most part of unorganised mate^ rial, they do not offer the same resistance to the growth of bacteria, when ift ^ ,i-.'-.,'â :â a few reach them, as a healthy cellu- lar tissue does. On micro- scopic exami- nation of the diseased valves the organisms are usually to be found in «- ----^T ».-^»,^Bajp- 'My enormous num- times tormmg an almost con- tinuous layer on the surface, or occurring in large masses or clusters in spaces in the vegetation (Fig. 75). By their action a certain amount of softening or breaking down of the vegetations occurs, and the emboli thus produced act as the carriers of infection to other organs, and give rise to secondary Fig. 75. â Section of a vegetation in ulcerative endocarditis, showing numerous staphylococci lying in the spaces. The lower portion is a fragment in process of separation. Stained by Gram's method and Bismarck-brown. X 600. Experimental. â Occasionally ulcerative endocarditis is produced by the simple intravenous injection of staphylococci and streptococci into the circula- tion, but this is a very rare occurrence. It often follows, however, when the valves have been previously injured. Orth and Wyssokowitsch at a com- paratively early date produced the condition by damaging the aortic cusps by a glass rod introduced through the carotid, and afterwards injecting staphylo-. Please note that these images are extracted from scanned page images that may have been digitally enhanced for readability - coloration
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