. Special pathology and therapeutics of the diseases of domestic animals. Veterinary medicine. 650 Actinomycosis. of abundant fibrous tissue niaj' cause the destruction of the actinomyces and thus bring about spontaneous recovery. Occasionally in loose connective tissue generally, especially in swine, but also in man, there occurs emigration of large numbers of leucocytes from the surrounding vessels as a result of the irritation produced by the parasite. Following this, large areas of the tissue surrounding the nodules undergo purulent softening, become confluent with other similar areas and
. Special pathology and therapeutics of the diseases of domestic animals. Veterinary medicine. 650 Actinomycosis. of abundant fibrous tissue niaj' cause the destruction of the actinomyces and thus bring about spontaneous recovery. Occasionally in loose connective tissue generally, especially in swine, but also in man, there occurs emigration of large numbers of leucocytes from the surrounding vessels as a result of the irritation produced by the parasite. Following this, large areas of the tissue surrounding the nodules undergo purulent softening, become confluent with other similar areas and thus produce large abscesses or fistulae which are always surrounded by a thick and usually very firm connective tissue AvalJ. Occasionally the suppurating process is induced by pyogenic bacteria which are met with most frequently in the pus of the larger abscesses. The mycelium of the parasite may penetrate the walls of the blood vessels and be transported to other regions of the body, thus giving rise to the development of metastatic tumors or abscesses such as are observed quite frequently in spongy bones, but also in the brain and other organs. Anatomical Changes. The seat and character of the anatomical changes vary with the species of animal. In cattle the tongue is most frequently affected, the maxillae coming second; tumors of the skin in the region of the liead and neck as well as larynx are also quite common, while the internal organs are only rarely Fig. 102. Aitiiioiiiycotic Ulcer on the Uorsum of the Tongue (food cavity) in an Ox. Actinomycosis of the tongue frequently takes the form of an ulcer situated immediately anteriorly to tlie dorsal promi- nence of the tongue (so called "food cavity"). In this con- dition there are one or more ovoid lesions, or transverse bands, consisting of loss of tissue substance; the bases of these lesions are surrounded by raised borders and are covered by numerous small depressions with ragged outlines. Hairs, o
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