. Annals of tropical medicine and parasitology. Parasites. 4o8 their course, remain negative in the meantime, though it is too soon to be confident that they will not relapse. Cases LVIII and LXIII were put on methyl emetine when it was found that a first course of alcresta had not cleared them up. Though we are dealing here with much smaller numbers, a comparison of the incidence of relapses after a second treatment brings out the same point as does Table II, that the weeks immediately following treatment are critical. Table IV. Of 9 cases that finished a 2nd treatment ... Of 8 cases, hi
. Annals of tropical medicine and parasitology. Parasites. 4o8 their course, remain negative in the meantime, though it is too soon to be confident that they will not relapse. Cases LVIII and LXIII were put on methyl emetine when it was found that a first course of alcresta had not cleared them up. Though we are dealing here with much smaller numbers, a comparison of the incidence of relapses after a second treatment brings out the same point as does Table II, that the weeks immediately following treatment are critical. Table IV. Of 9 cases that finished a 2nd treatment ... Of 8 cases, hitherto negative, observed at the end of the ist week after treatment Of 2 cases, hitherto negative, observed at the end of the 2nd week after treatment Of 2 cases, hitherto negative, observed at the end of the -?rd week after treatment. Positive • This negative case was observed to be negative still at the end of the 4th, 5th and 7th weeks. Of two cases that finished a ^/lird treatrnent, both were negative at the end. By the end of the first week one had relapsed. This relapsing case belongs rightly, therefore, to the category of refractory cases, considered below. The negative case remained negative at the end of the second, third, fourth, fifth, sixth and seventh weeks. (J)) In this ' refractory' group there are four cases (IV, VI, XXIII, and XXXI) which have so far defied treatment with alcresta. One of them has been mentioned in Table IV as relapsing after a second and third treatment; the other three have not been included in Tables III and IV, as their treatment has been practically continuous. Cases VI, XXIII and XXXI have now been put on methyl emetine, kindly provided by Dr. H. H. Dale, , of the Medical Research Committee; and it remains to be seen whether emetine in this form will effect a Please note that these images are extracted from scanned page images that may have been digitally enhanced for readability - coloration and appearance of these illust
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