. The endocrine organs; an introduction to the study of internal secretion . itarism) remains small (fig. 79). This is generally associated withmarked adiposity, so that the weight of the body may be large relativelyto the height. Sexual development is delayed and may remain consider-ably in abeyance, producing a more or less permanent condition of sexualinfantilism. In the female the menses are irregular or absent, and in bothsexes there is deficient development of secondary sexual characters suchas the hair on the face (in the male) and over the pubes in both hair as occurs in the
. The endocrine organs; an introduction to the study of internal secretion . itarism) remains small (fig. 79). This is generally associated withmarked adiposity, so that the weight of the body may be large relativelyto the height. Sexual development is delayed and may remain consider-ably in abeyance, producing a more or less permanent condition of sexualinfantilism. In the female the menses are irregular or absent, and in bothsexes there is deficient development of secondary sexual characters suchas the hair on the face (in the male) and over the pubes in both hair as occurs in the last-mentioned situation in the male does notextend to the umbilicus as is usual in that sex, but assumes the dispositioncharacteristic of the female, being limited to the mons veneris. On theother hand, the hair of the head is generally abundant. Nor is thecharacter of the trichosis the only sign of feminism in subjects affected byhypopituitarism. They usually have a broad pelvis, a certain amount ofgenu valgum, rounded limbs, small feet and hands with tapering fingers,. FIG. 78.—Case of bulletwound of pituitary.(Madelung.) Clinical Evidence regarding Functions of Pituitary 111 and occasionally well-marked mammary development. Skiagrams of thebones generally exhibit persistent epiphysial lines (fig. 80). The skin issmooth and delicate and free from moisture. The nails are small andthin, and the crescents at their base are absent. The tendency to adiposity is attributable by Gushing to deficiency ofposterior lobe secretion. This deficiency is usually associated with unusualtolerance to sugar and an excessive assimilative power for carbohydrates,which become transformed into fat andthus produce adiposity. A subnormal body - temperature isgenerally present with the above symp-toms, as well as low arterial tensionand a slow pulse; there is also oftendrowsiness and Sometimesevidences of psychic derangements andoccasionally a tendency to epilepsy havebeen described. H
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