. Medical diseases of infancy and childhood. of whom is reprrKluced in Fig. 17. In this case the orbits wereshallow, the sderotics visible al)ove the cornea, and the eyeballs de-pressermous frontal bosses, while theparietal bones were pushed outward and much thickened at their 200 SYPHILIS. upper edges. Children suffering from late syphilis are backward,and sometimes distinctly deficient in intellect. Bone lesions, periosteal or epiphysial, occur in a very large propor-tion of all cases of inherited syphilis. According to Wagner, Birch-Hirschfeld, and other pathologists, epiphysial changes are


. Medical diseases of infancy and childhood. of whom is reprrKluced in Fig. 17. In this case the orbits wereshallow, the sderotics visible al)ove the cornea, and the eyeballs de-pressermous frontal bosses, while theparietal bones were pushed outward and much thickened at their 200 SYPHILIS. upper edges. Children suffering from late syphilis are backward,and sometimes distinctly deficient in intellect. Bone lesions, periosteal or epiphysial, occur in a very large propor-tion of all cases of inherited syphilis. According to Wagner, Birch-Hirschfeld, and other pathologists, epiphysial changes are present inall infants who die while suffering from the disease. Osteoplastic periostitis producing a layer of porous osseous tissueoccurs in the foetus, and may be present at birth. The process maycontinue after birth, rendering the shafts thick, but true sub-peri-osteal nodes of the long bones, recognizable during life, are exceed- FiG. Hydrocephalus in a syphilitic infant, showing bossing of cranial bones. ingly rare in infants, and rare in older children. On the bones ofthe skull thickenings of periosteal origin are very common. Theyoccur most often on the frontal and parietal bones, close to the ante-rior fontanelle, and not, as in rickets, on the frontal and parietaleminences. When large they form thick bosses on either side of thefontanelle, and if the thickening extends on to the forehead so thatthe site of the interfrontal suture is marked by a deep groove, theappropriateness of the descriptive term, ^^ natiform skull,^^ applied tothe condition by Parrot, is very striking. Post mortem the thickenedbone is found to be soft and porous, so that it can easily be cut with INHERITED SYPHILIS. 201 a knife, and vascular. The mariiin of tlie boss may he well defined,or the larger part, or the whole of the bone or, indeed, of the skull,may be thick and vascular, the changes being greatest at the lesion does n


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Keywords: ., bookcentury1900, bookdecade1900, booksubjectchildren, bookyear190