. Medical communications of the Massachusetts Medical Society. Fig. 5. Chart showing polyuria prolonged over a period of six months after hypophysial stalk separation. Protocol. Seven kilo, fox-terrier. Dec. 18: Stalk separation with fragmentary anterior lotremoval. Polyuria observed on the six observations during the succeeding ten days and onoccasions when the amount was measured during the succeeding six months, the animal meanwlacquiring the characteristic adiposity with drowsiness, subnormal temperature and so on, of hypephysial insufficiency. _ A marked increase of polyuria followed the


. Medical communications of the Massachusetts Medical Society. Fig. 5. Chart showing polyuria prolonged over a period of six months after hypophysial stalk separation. Protocol. Seven kilo, fox-terrier. Dec. 18: Stalk separation with fragmentary anterior lotremoval. Polyuria observed on the six observations during the succeeding ten days and onoccasions when the amount was measured during the succeeding six months, the animal meanwlacquiring the characteristic adiposity with drowsiness, subnormal temperature and so on, of hypephysial insufficiency. _ A marked increase of polyuria followed the injection, on June 14, of 10 ;of a one per cent solution of anterior lobe emulsion of bovine gland. Animal sacrificed on June 1< POLYURIAS OF HYPOPHYSIAL ORIGIN. 35 Schafer6 in the course of some experiments on the effectof glandular transplants in non-hypophysectomized animals,observed that the subcutaneous implantation of the pos- June, <qo<j. Fig. 6. Chart showing persistent polyuria following posterior lobe reimplanta-tion in the cerebral subcortex after excision. Polyuria promptly inter-rupted after excision of the transplant on the fifteenth day. terior lobe from one animal to another causes a transientpolyuria, which subsides in a few days, coincident pre-sumably with the absorption of the secretory products con-tained in the implanted tissue. It would appear, moreover, 36 CONCERNING DIABETES INSIPIDUS AND THE from certain observations made by Stiles, under Schafersdirection, that the posterior lobe substance given by mouth 130^


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Keywords: ., bookcentury1900, bookdecade1910, booksubjectmedicine, bookyear191