A treatise on the diseases of the nervous system . ight side being the seat of profound muscularatrophy. On post-mortem examination it was found that the right an-terior horn of gray matter in the dorsal and cervical regions was theseat of degenerative changes in the nerve-cells, many of which had dis-appeared. The horn was markedly diminished in size. These changesare shown in the accompanying figure (Fig. 86) from Pierret—a, theposterior roots ; b, the internal radicles, the sclerosis being limited totheir area ; <?, the right anterior horn of gray matter atrophied. Thisassociation of mus


A treatise on the diseases of the nervous system . ight side being the seat of profound muscularatrophy. On post-mortem examination it was found that the right an-terior horn of gray matter in the dorsal and cervical regions was theseat of degenerative changes in the nerve-cells, many of which had dis-appeared. The horn was markedly diminished in size. These changesare shown in the accompanying figure (Fig. 86) from Pierret—a, theposterior roots ; b, the internal radicles, the sclerosis being limited totheir area ; <?, the right anterior horn of gray matter atrophied. Thisassociation of muscular atrophy with sclerosis of the posterior root-zones is to be explained by the fact, first pointed out by Kolliker,1 thatsome of the internal fibres of the posterior roots pass toward the ante-rior horns of gray matter, and can be traced as far as the large cellsforming the external group. The connection of the fibres of the pos-terior roots with the anterior horns of gray matter is also referred toby Lockhart Clarke2 and Fio. Treatment.—It must be remembered that locomotor ataxia oftenspontaneously remits in the violence of its symptoms. Indeed, the re-mission may at times amount to almost a complete intermission. Buttaking this fact into full consideration, I am quite sure that the diseaseis not in every case uninfluenced by medical treatment. A great manymedicines have been recommended, and numbers of cures have been re-ported. Careful inquiry, however, suffices to show either that the al- 1 A Manual of Human Histology, Sydenham Society Translations, vol. i., 1853,p. 415. 2 Philosophical Transactions, 1853. 3 Striekers Manual of Histology, American edition, New York, 1872, p. 645. PROGRESSIVE LOCOMOTOR ATAXIA. G33 ieged cures were merely instances of more or less complete remission,or that the cases were really not examples of the disease in even mention the assumed remedies would be profitless labor. In the very earliest period of the dise


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Keywords: ., bookcentury1800, bookdecade1880, booksubjectnervoussystem, bookye