. Control mechanisms in cellular processes. Cytology; Biochemistry. 152 CONTROL MECHANISMS IN CELLULAR PROCESSES Eys and Warnock, 1959) (Fig. 5-1). With measurable DPNH levels restored, the removal of glycolytically reduced DPN can be a rate- limiting step, which determines the rate of aerobic lactic acid pro- duction. 5 10 UNITS HEXOKINASE ADDED Fig. 5-1. The effect of the addition of hexokinase and 2-deoxyglucose on aerobic glycolysis of fructose diphosphate. All flasks contained 30 //mole of 2-deoxyglucose. One unit of hexokinase is that amount of enzyme which phos- phorylates 1 /imol
. Control mechanisms in cellular processes. Cytology; Biochemistry. 152 CONTROL MECHANISMS IN CELLULAR PROCESSES Eys and Warnock, 1959) (Fig. 5-1). With measurable DPNH levels restored, the removal of glycolytically reduced DPN can be a rate- limiting step, which determines the rate of aerobic lactic acid pro- duction. 5 10 UNITS HEXOKINASE ADDED Fig. 5-1. The effect of the addition of hexokinase and 2-deoxyglucose on aerobic glycolysis of fructose diphosphate. All flasks contained 30 //mole of 2-deoxyglucose. One unit of hexokinase is that amount of enzyme which phos- phorylates 1 /imole of glucose per minute. The following experiments performed by Mr. Warnock in this laboratory illustrate this. In mouse liver homogenates the lactic acid production from fructose diphosphate can be lowered if microsomes and cytochrome c are added (Table 5-3). This effect is seen only. Please note that these images are extracted from scanned page images that may have been digitally enhanced for readability - coloration and appearance of these illustrations may not perfectly resemble the original Bonner, David M; Society of General Physiologists; Suskind, Sigmund R. New York, Ronald Press
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