. The practice of pediatrics. the first week; in 3,in the second week, and in 1, in the third week. In 8 the serum had nomarked effect. Of these, 3 were in the first week, the other 5 being latechronic cases. One patient in the late chronic stage began to improve after one doseof the serum and made a rapid convalescence. This would indicate thatimprovement is always possible in the presence of meningococci. More Recent Methods in the Use of Serum.—Since the introductionof the antimeningitic serum in the spring of 1907 by Flexner, the mortal-ity in infants has fallen from 95 per cent, to betwee
. The practice of pediatrics. the first week; in 3,in the second week, and in 1, in the third week. In 8 the serum had nomarked effect. Of these, 3 were in the first week, the other 5 being latechronic cases. One patient in the late chronic stage began to improve after one doseof the serum and made a rapid convalescence. This would indicate thatimprovement is always possible in the presence of meningococci. More Recent Methods in the Use of Serum.—Since the introductionof the antimeningitic serum in the spring of 1907 by Flexner, the mortal-ity in infants has fallen from 95 per cent, to between 40 and 50 per in view of this remarkable reduction in mortality, one must searchfor further improvement. The old method of serum treatment isundoubtedly inaccurate, and one is not able to judge with any degreeof accuracy the quantity of serum injected, nor is the operator able topredict any untoward symptoms which might arise during the processof injection. It is true that few fatalities, as far as we know, have. Fig. 73.—Apparatus for injecting serum. CEREBROSPINAL MENINGITIS 545 occurred from the injection of too large a quantity of serum, but animprovement on the old procedure is welcome. During the recentDallas epidemic Sophian, of New York, contrived a means of controllingthe injection and frequently indicating the quantity of cerebrospinalfluid that can be withdrawn. Theoretically, one would expect a return to the original pressure ofthe cerebrospinal fluid on injecting a volume of serum equal to thequantity of fluid withdrawn, but this is certainly not the case. Occasion-ally one may inject even larger quantities of serum than fluid withdrawn,but the pressure readings of the fluid are frequently lower than beforethe removal. In view of this unreliability of pressure in the spinalfluid and dangers attached to the old method, Sophian, in 600 lumbarpunctures, used the blood-pressure as an index, with almost uniformresults. Procedure.—An assistant takes the
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Keywords: ., bookcentury1900, bookdecade1910, bookid39002, booksubjectchildren
