. Ciba Foundation colloquia on ageing. Old age; Aging; Animals -- growth & development. Studies of Human Organ System Function 75 response to a standard exercise (Master and Oppenheimer, 1929) was ostensibly designed to disclose coronary arterio- sclerosis in individuals with equivocal or no clinical evidences of cardiac disease and in whom the electrocardiogram at rest was normal. Agewise differences in the normal electrocardio- graphic response to exercise have been reported by our laboratory (Silver and Landowne, 1953), as well as by others none slight—* moderate marked-* extreme^. m 3%


. Ciba Foundation colloquia on ageing. Old age; Aging; Animals -- growth & development. Studies of Human Organ System Function 75 response to a standard exercise (Master and Oppenheimer, 1929) was ostensibly designed to disclose coronary arterio- sclerosis in individuals with equivocal or no clinical evidences of cardiac disease and in whom the electrocardiogram at rest was normal. Agewise differences in the normal electrocardio- graphic response to exercise have been reported by our laboratory (Silver and Landowne, 1953), as well as by others none slight—* moderate marked-* extreme^. m 3%& all ages Fig. 1. Gross morphological total and agewise incidence of coronary sclerosis, graded as to severity and expressed as percentage of the corresponding age group. Data from over 3,000 consecutive male autopsies reported by Willius, Smith and Sprague (1933). The number of cases in each age group is indicated at top of the column. (Master, Friedman and Dack, 1942; Simonson and Keys, 1956). Although there may have been important differences in the manner and effectiveness of selection of these "normals", it would have to be admitted that they do not represent "pure" normals, but are carefully selected subjects in whom, statistically, coronary sclerosis is present with increasing agewise incidence and severity. To have obtained a lesser contaminating incidence of disease, one would need to have known at least the information which was supposed to result. Please note that these images are extracted from scanned page images that may have been digitally enhanced for readability - coloration and appearance of these illustrations may not perfectly resemble the original Ciba Foundation; Wolstenholme, G. E. W. (Gordon Ethelbert Ward). Boston, Little, Brown


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Keywords: ., bookcentury1900, bookpublish, booksubjectaging, booksubjectoldage