. Biology of the laboratory mouse. Mice as laboratory animals; Mice; Animals, Laboratory; Mice. SUSCEPTIBILITY \ NON-SUSCEPTIBILITY. SUSCEPTIBILITY GENE PRESENT m SUSCEPTIBLE I NON-SUSCEPTIBLE PERCENT SUSCEPTIBLE Fig. 127.—Diagram showing the inheritance of susceptibility to transplanted tumors where susceptibility is due to the presence of a single dominant gene. Characters dependent upon one pair of genes.—It is, of course, well known that Mendelian inheritance when one pair of genes is involved gives a 3:1 ratio in F2, in this case 3 susceptible mice to i non-susceptible mouse (Fig. 12
. Biology of the laboratory mouse. Mice as laboratory animals; Mice; Animals, Laboratory; Mice. SUSCEPTIBILITY \ NON-SUSCEPTIBILITY. SUSCEPTIBILITY GENE PRESENT m SUSCEPTIBLE I NON-SUSCEPTIBLE PERCENT SUSCEPTIBLE Fig. 127.—Diagram showing the inheritance of susceptibility to transplanted tumors where susceptibility is due to the presence of a single dominant gene. Characters dependent upon one pair of genes.—It is, of course, well known that Mendelian inheritance when one pair of genes is involved gives a 3:1 ratio in F2, in this case 3 susceptible mice to i non-susceptible mouse (Fig. 127). Characters dependent upon two pairs of genes.—If now we suppose that two genes, A and B, are needed simultaneously to produce susceptibility we should have a ratio, not of 3:1, but of 9:7 or :1 (Fig. 128). Characters dependent upon three pairs of genes.—If we continue this principle to a character dependent upon the simultaneous presence of 3 genes, the ratio will change still further (Fig. 129).. Please note that these images are extracted from scanned page images that may have been digitally enhanced for readability - coloration and appearance of these illustrations may not perfectly resemble the original Roscoe B. Jackson Memorial Laboratory; Little, Clarence C. (Clarence Cook), b. 1888; Snell, George D. (George Davis), 1903-; Dingle, John H. (John Holmes), 1908-. Philadelphia, The Blakiston company
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