The cell in development and inheritance . in the configurationof the network, and he described the nucleus as showing a distinctpolarity having a pole corresponding with the point toward whichthe apices of the chromosomes converge { toward the centrosome),and an antipole (Gegenpol) at the opposite point { toward theequator of the spindle) (Fig. 22). Rabls hypothesis was preciselyformulated and ardently advocated by Boveri in 1887 and 1888, andagain in 1891, on the ground of his own studies and those of VanBeneden on the early stages of Ascaris. The hypothesis was supported MORPHOLOGICA


The cell in development and inheritance . in the configurationof the network, and he described the nucleus as showing a distinctpolarity having a pole corresponding with the point toward whichthe apices of the chromosomes converge { toward the centrosome),and an antipole (Gegenpol) at the opposite point { toward theequator of the spindle) (Fig. 22). Rabls hypothesis was preciselyformulated and ardently advocated by Boveri in 1887 and 1888, andagain in 1891, on the ground of his own studies and those of VanBeneden on the early stages of Ascaris. The hypothesis was supported MORPHOLOGICAL COMPOSITION OF THE NUCLEUS 295 by extremely strong evidence, derived especially from a study of ab-normal variations in the early development of Ascaris, the force ofwhich has, I think, been underestimated by the critics of the of this evidence may here be briefly reviewed. In some cases,through a miscarriage of the mitotic mechanism, one or both of thechromosomes destined for the second polar body are accidentally left.


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Keywords: ., bookcentury1900, bookdecade1900, booksubjectcells, bookyear1902