. Endocrinology. egard endocrine therapy asa panacea for mental deficiency would curtail what legitimateuse it may subserve. BIBLIOGKAPHV 1. Konikow, M. J.: A case of retarded mentality in a child treated byorganotherapy. Endpcrin. (Los Angeles), 1922, «. 21S-220. 2. Raeder. O. J.: Endocrinology in the feebleminded in one hundredautopsied cases. BuH. Am. Ass. Study of the Feebleminded, June, 1920. 3. Timme, W.: Clinical endocrinology. Neurol. Bull., 1921, 3, 3. 4. Timme, W.: The Mongolian idiot. Arch. Neurol. & Psychiat.(Chicago), 1921, 5, 568. EXPERIMENTAL INVESTIGATION OF THE VALUE OFTHE VAR
. Endocrinology. egard endocrine therapy asa panacea for mental deficiency would curtail what legitimateuse it may subserve. BIBLIOGKAPHV 1. Konikow, M. J.: A case of retarded mentality in a child treated byorganotherapy. Endpcrin. (Los Angeles), 1922, «. 21S-220. 2. Raeder. O. J.: Endocrinology in the feebleminded in one hundredautopsied cases. BuH. Am. Ass. Study of the Feebleminded, June, 1920. 3. Timme, W.: Clinical endocrinology. Neurol. Bull., 1921, 3, 3. 4. Timme, W.: The Mongolian idiot. Arch. Neurol. & Psychiat.(Chicago), 1921, 5, 568. EXPERIMENTAL INVESTIGATION OF THE VALUE OFTHE VARIOUS (^OxMMERCIAL OVARIAN EXTRACTS* SAMUEL H. GEIST, , , and WILLIAM HARRIS, Gynecolog^ist, Associate in Pathology, Mt. Sinai Hospital. Much has been done and written on the therapeutic value ofthe numerous endocrine preparations, but unfortunately, mostof the work is empirical in nature. While it is true that manyvaluable facts have l)een ae(|uirpd in tliis way. still it seems that. of Parke-Davis the mass of evidence is based on the interpretations of the investi-gators and the statements of the patients, which statements maybe influenced psychically. 42 VALUE OF OVARIAN EXTRACTS It would be much more advantageous if we could experi-mentally demonstrate the clinical value or a definite physiologicalactivity of the commercial endocrine products, and be able atany time to duplicate the results. There are many objections to the empirical method in addi-tion to those mentioned above, for we know that it is extremelydifficult at the present time to classify accurately the varioustypes of endocrinological syndromes, with few exceptions, and inaddition, the overlapping of groups makes the results of investi-gation more uncertain. Certain preparations, Ave can administer with a fair degreeof precision. The thyroid, the adrenal and the posterior pituitary
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