. Medical diagnosis for the student and practitioner. epresents defective hemogenesis and signifies degeneration, beingfound as a prevailing type of erythroblast only in primary pernicious anemia,nitro-benzol poisoning, and bothriocephalus anemia. In any severe anemia anoccasional cell of this type may be found. I The microblast (5 to 6ju) presents essentially the same appearance, aside Ifrom size, as the normoblast and has the same clinical significance. Unusual Forms.—Various mixed types are encountered (mesoblasts) |which defy differentiation, showing contradictions in size and staining Mes
. Medical diagnosis for the student and practitioner. epresents defective hemogenesis and signifies degeneration, beingfound as a prevailing type of erythroblast only in primary pernicious anemia,nitro-benzol poisoning, and bothriocephalus anemia. In any severe anemia anoccasional cell of this type may be found. I The microblast (5 to 6ju) presents essentially the same appearance, aside Ifrom size, as the normoblast and has the same clinical significance. Unusual Forms.—Various mixed types are encountered (mesoblasts) |which defy differentiation, showing contradictions in size and staining ; some, which Da Costa regards as immature normoblasts, show apale nucleus with acid stain stippling and polychromatophilic others, large in size, contain a small deeply basic staining nucleus andfaintly stained protoplasm. These he would classify as megaloblasts. « 128 MEDICAL DIAGNOSIS Differentialvalue. Significance. Ring bodies. Of slightimportance. Jolly bodies. Instrumentsand technic. Pipettes, Fig. 37.— Basophilicstippling and Cabots ringbodies. (After Cabot,Ewing and DaCosta.) Basophilic Erythrocytes may be encountered, showing fine, coarse, spicularor even ovoid granules of regular or irregular distribution. These cells occurin lead poisoning, in chlorosis with intestinal auto-intoxication and practicallyall of the profound or pernicious forms of anemia, but are absent in the anemiaof renal and hepatic disease, the acute infections, syphilis and Cabot has described and drawn extraordinary intra- and extra-cellularring bodies in lead poisoning, pernicious anemia and lymphatic have also been found by Da Costa in theprofound anemias of sepsis. Basic ring bodieswere previously described by Strauss and Rohn-stein. It is now known that these for. the mostpart take the acid stain of Wrights solution,rarely the blue. Maurer?s Spots.—These bodies appear in theinfected erythrocytes of victims of esti
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Keywords: ., bookcentury1900, bookdecade1920, booksubjectdiagnos, bookyear1922
