. Fig. 12.—Showing the infiltration of mononuclear cells in the spinal ganglion. EXPERIMENTAL POLIOMYELITIS 477 EXPERIMENTAL POLIOMYELITIS.* BY SIMON FLEXNER, M. York Mr. President, Ladies and Gentlemen: I am not a member of this society and I regard it, there-fore, as a great distinction to be asked to come here and presentto you the results of an experimental study into the causationand pathology of epidemic poliomyelitis. You need not bereminded that this state has suffered severely for three yearsfrom an epidemic of this disease. I am not very familiar withthe extent to


. Fig. 12.—Showing the infiltration of mononuclear cells in the spinal ganglion. EXPERIMENTAL POLIOMYELITIS 477 EXPERIMENTAL POLIOMYELITIS.* BY SIMON FLEXNER, M. York Mr. President, Ladies and Gentlemen: I am not a member of this society and I regard it, there-fore, as a great distinction to be asked to come here and presentto you the results of an experimental study into the causationand pathology of epidemic poliomyelitis. You need not bereminded that this state has suffered severely for three yearsfrom an epidemic of this disease. I am not very familiar withthe extent to which the disease prevailed in this region, but itappeared in Greater New York in 1907 and it reappeared there,but luckily on a less extensive scale, in 1909. Up to recently wehave had no satisfactory knowledge of the casuation of thisvery destructive disease. Indeed, our ignorance has been soprofound that we had no knowledge as to how the poison gainedaccess to the body, and we have, therefore, been unable a


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