. Text-book of normal histology: including an account of the development of the tissues and of the organs. Primary embryonal cartilage repre-senting one of the carpal bones : /,perichondrium, or primary periosteum ;«, nutrient canals extending from C2 NORMAL HISTOLOGY. the periosteum ; where bone is developed directly from the periosteum,and without being mapped out by primary cartilage, the process isspoken ol as intermembranous bone-formation, although differ-ing in no important respect from that pnxlucing the periosteal bone. Endochondral Bone. The first indications of the f
. Text-book of normal histology: including an account of the development of the tissues and of the organs. Primary embryonal cartilage repre-senting one of the carpal bones : /,perichondrium, or primary periosteum ;«, nutrient canals extending from C2 NORMAL HISTOLOGY. the periosteum ; where bone is developed directly from the periosteum,and without being mapped out by primary cartilage, the process isspoken ol as intermembranous bone-formation, although differ-ing in no important respect from that pnxlucing the periosteal bone. Endochondral Bone. The first indications of the future pro-found changes within the solid cartilage correspond in position to the so-called centres of ossification,60. and consist in an increase in the size g,%9^i^H of the embryonal cartilage-cells, as well ^ »?-«*f as in the amount of intercellular sub- stance separating the cell-nests, followedby a characteristic rearrangement ofthe enlarged cells into vertical rowsor columns ; in the matrix between andaround these columnar groups a cal-careous deposit subsequently takes- :®®®^J»f^j^^./ place. These enlarged cartilage-cells,«â - â¢>i,^-<*e-^* surrounded by the calcified matrix, are Developing boneâcentre of ossifica- . 1 ^ â_:.ââ
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