. The biology of senescence. Old age; Aging; Longevity. The Nature and Criteria of Senescence. YEARS Fig. 13.—Irish Wolfhounds. Survival of 67 individuals from 12 months of age—sexes combined. Line—whole sample, annual totals. Points—38 in- dividuals whose exact date of death was known, to scale (data from Miss D. Gardner). histological appearances of many kinds, and estimations of general or special metabolism are of value within sharply- defined limits, but all are subject to considerable variation apart from the general senile process. In retarded Gladocera, for example, where mean life-spa
. The biology of senescence. Old age; Aging; Longevity. The Nature and Criteria of Senescence. YEARS Fig. 13.—Irish Wolfhounds. Survival of 67 individuals from 12 months of age—sexes combined. Line—whole sample, annual totals. Points—38 in- dividuals whose exact date of death was known, to scale (data from Miss D. Gardner). histological appearances of many kinds, and estimations of general or special metabolism are of value within sharply- defined limits, but all are subject to considerable variation apart from the general senile process. In retarded Gladocera, for example, where mean life-span is artificially prolonged by post- poning growth, the heart rate fails to decline before death to the low levels normally found in old age (Ingle, Wood and Banta, 1937). Minot (1908), Hertwig and others considered that a steady decrease in the nucleocytoplasmic ratio was a general feature of ageing in organisms, a suggestion which has not been upheld by later work, and which would today require trans- lation into more precise biochemical terms. Dehydration was also formerly regarded as a general senile phenomenon. From a recalculation of older data, however, and from fresh material, 29. Please note that these images are extracted from scanned page images that may have been digitally enhanced for readability - coloration and appearance of these illustrations may not perfectly resemble the original Comfort, Alex, 1920-. New York, Rinehart
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