British medical journal . tscapacity to agglutinate sheeijs cells but had lost the powerto agglutinate human cells. As in the case of the bacterialagglutinins, therefore, the haeiuagghitinius are specilic fordifferent varieties of red cells, and the same serum maycontain a number of haemagglutinins. Fig. V shows the :result of this experiment. The Action of Hacmagylutinaling Scrums on WholeForeign Blootl— /Jrop and Pool Method. : So far we have only doalt with the inliuciice »f dilTcreijfcantiseptics in favouring or inhibiting the tendency of red i)EC. 8, 1917] IHE HAEMAGGLUTININ REACTION. rTH


British medical journal . tscapacity to agglutinate sheeijs cells but had lost the powerto agglutinate human cells. As in the case of the bacterialagglutinins, therefore, the haeiuagghitinius are specilic fordifferent varieties of red cells, and the same serum maycontain a number of haemagglutinins. Fig. V shows the :result of this experiment. The Action of Hacmagylutinaling Scrums on WholeForeign Blootl— /Jrop and Pool Method. : So far we have only doalt with the inliuciice »f dilTcreijfcantiseptics in favouring or inhibiting the tendency of red i)EC. 8, 1917] IHE HAEMAGGLUTININ REACTION. rTHE BRiTisa 753 blood corpuscles to climiii togetlici- under suitable condi-tions. Before \vc draw any inferences as to the toxicaction of these reagents on tlic scrum, the red corpusclesor the leucocytes, it is necessary to ascertain what actiontViffcrentscnims of different agglutinative capacity exer-cise on the whole blood of another individual X. J. B.) |wilhout the addition of any antiseptic (Fig. Villi. jBlooo CELL. OR t-lQ PURtS One or more drops of Die serum to be tested are placed withina vaseline or plasticins cell. Into the centre of tlie little jroolof serum so enclosed a small drop of blood from the linger isallowed to fall: the cell is closed by a cover-slip. After incuba-tion the cover-slip and cell wail of this emigrating chamber arcremoved, tljcblood clot and serum aregcntl> washed awa> withnormal saline, and the film of emigrated leucocytes andstained with 1 per cent, iodine solution. The extent to whichthe toxic or agglutinative action of the scrum affects theactivities of the leucocytes from the periphery towards thecentre of the drop of blood affords a rough quantitative test ofthe toxic capacity of llie serum by which the drop of bloodis. bathed, and tile extent to which the foreign serum hasneutralized the normal serum of the blood tested. If the forcig7i serum used be an iso-haeinagglatinatingscritm then the (C. J. red blood cells clump


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Keywords: ., bookcentury1800, bookdecade1850, booksubjectmedicine, bookyear185