. Pathology and bacteriology [electronic resource]. Ophthalmology; Eye; Eye; Bacteriology; Ophthalmology; Eye; Bacteriology; Eye. COLOBOMA OF THE IRIS lOI That aniridia is due to some mechanical obstruction to the growth inwards of the secondary optic vesicle, which forms the posterior layers of the iris, seems probable, be- cause, the pigment epithelium on the back of the small rudimentary iris in these cases is often found in excess and plicated. The frequent association of anterior polar cata- ract with aniridia also suggests prolonged contact of lens and Fig. 64.—Shows the microsc
. Pathology and bacteriology [electronic resource]. Ophthalmology; Eye; Eye; Bacteriology; Ophthalmology; Eye; Bacteriology; Eye. COLOBOMA OF THE IRIS lOI That aniridia is due to some mechanical obstruction to the growth inwards of the secondary optic vesicle, which forms the posterior layers of the iris, seems probable, be- cause, the pigment epithelium on the back of the small rudimentary iris in these cases is often found in excess and plicated. The frequent association of anterior polar cata- ract with aniridia also suggests prolonged contact of lens and Fig. 64.—Shows the microscopical appearances of the front part of a microph- thalmic eye with coloboma of the iris. Note the presence of blood-vessels in the anterior layers of the cornea. Case recorded R, Lond. Ophth. Hosp. Rep., XII, 1889, 289. Coloboma of the Iris.—coloboma of the iris is a defi- ciency in the tissue of the iris causing the pupil to be altered in shape (Fig. 64). It is one of the commonest malforma- tions of the eye. The term pseudo-coloboma of the iris is applied to cases in which a portion only of the stroma of the iris is deficient, the deeper layers being present and left exposed. In the large majority of cases of coloboma of the iris the defect is situated in its lower half, either directly down- ward, or downward with a slight inclination inward or outward; , in the position of the fetal cleft. It has, however, been met with in exceptional cases upward, in- ward, and outward. Two colobomata of the iris may in rare cases occur in the same eye, and in some cases more than half the iris has. Please note that these images are extracted from scanned page images that may have been digitally enhanced for readability - coloration and appearance of these illustrations may not perfectly resemble the original Collins, E. Treacher (Edward Treacher), 1862-1937; Mayou, M. Stephen (Marmaduke Stephen), 1876-1934; Pyle, Walter L. (Walter Lytle), 1871-1921, editor; University Coll
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