Practical hormone therapy : a manual of organotherapy for general practitioners . ecre-tin theory, so long discounted by certain Russian andItalian physiologists, is no longer so mitenable. Sawitchand Zeliony,^* reporting a series of experiments whichwere carried out in the physiological laboratory of theMilitary Medical Academy in St. Petersburg, have estab-lished the essential accuracy of Edkinss contention thatnormal gastric secretion is due to the co-operation of atleast two factors—the one a nervous element induced by The Secretins and Pyloro-Duodenal Extracts 63 the stimulation of the mu
Practical hormone therapy : a manual of organotherapy for general practitioners . ecre-tin theory, so long discounted by certain Russian andItalian physiologists, is no longer so mitenable. Sawitchand Zeliony,^* reporting a series of experiments whichwere carried out in the physiological laboratory of theMilitary Medical Academy in St. Petersburg, have estab-lished the essential accuracy of Edkinss contention thatnormal gastric secretion is due to the co-operation of atleast two factors—the one a nervous element induced by The Secretins and Pyloro-Duodenal Extracts 63 the stimulation of the mucosa of the mouth or by theawakening of the appetite through psychic chamiels, andthe other a chemical factor dependent on the elaborationof a hormone which acts as a chemical messenger to allparts of the stomach through humoral paths, and whoseeffects linger long after the psychic stimulus has dis-appeared. In his book on The Action of Medicines,* Bruntonillustrates his statements by means of a diagram (Fig. 6).This diagram (for permission to use which I have cordially No^O. orX Fig. 6.—Di.^gram to illustkatb the Chemicwl dckin-gGastuic Secketiox. to thank this distinguished therapeutist) shows that itwas hardly possible, before the discovery of the hormones,to explain the phenomena of gastric digestion withoutpresupposing the presence of an indefinite entity. It isevident that in this diagram, which is intended to illus-trate the chemical changes during secretion, the unknownquantity, or X, is no other than secretin, or, rather, inthis particular case, gastrin, or gastric secretin. A very similar, and perhaps identical, hormone isprobably produced by the spleen, the function of which * Kdiliuu dl 18J7, \\ 50. 64 Practical Hormone Therapy is to stimulate the digestive glands to do their normalwork. This splenic hormone has been proved by numer-ous physiologists to have a part in the activation oftrypsinogen. The Physiology of Secretin Action.—Dixon and Hamill^^
Size: 1743px × 1434px
Photo credit: © The Reading Room / Alamy / Afripics
License: Licensed
Model Released: No
Keywords: ., bookcentury1900, bookdecade1910, bookpublisherlondo, bookyear1914
